Zeolite NaY promotes 1,3-dipolar cycloaddition of ethyl diazoacetate to alkynes having an electron-withdrawing group to afford the corresponding functionalized pyrazoles in high yields. The activation of the dipolarophile inside the pores of NaY is proposed based on the 13C MAS NMR analysis.
Pyrazole derivatives R 0180 1,3-Dipolar Cycloaddition of Ethyl Diazoacetate to Alkynes in the Pores of Zeolite NaY. -Based on a 13 C-NMR experiment it is proposed that the activation of the dipolarophile occurs inside the pores of zeolite NaY. -(KOBAYASHI, K.; IGURA, Y.; IMACHI, S.; MASUI, Y.; ONAKA*, M.; Chem. Lett. 36 (2007) 1, 60-61; Dep. Chem., Grad. Sch. Arts Sci., Univ. Tokyo, Meguro, Tokyo 153, Japan; Eng.) -K. Schneider 26-112
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