Introduction Measles is targeted for elimination in the World Health Organization African Region by the year 2020. In 2011, Kenya was off track in attaining the 2012 pre-elimination goal. We describe the epidemiology of measles in Kenya and assess progress made towards elimination. Methods We reviewed national case-based measles surveillance and immunization data from January 2003 to December 2016. A case was confirmed if serum was positive for anti-measles IgM antibody, was epidemiologically linked to a laboratory-confirmed case or clinically compatible. Data on case-patient demographics, vaccination status, and clinical outcome and measles containing vaccine (MCV) coverage were analyzed. We calculated measles surveillance indicators and incidence, using population estimates for the respective years. Results The coverage of first dose MCV (MCV1) increased from 65% to 86% from 2003-2012, then declined to 75% in 2016. Coverage of second dose MCV (MCV2) remained < 50% since introduction in 2013. During 2003-2016, there were 26,188 suspected measles cases were reported, with 9043(35%) confirmed cases, and 165 deaths (case fatality rate, 1.8%). The non-measles febrile rash illness rate was consistently > 2/100,000 population, and “80% of the sub-national level investigated a case in 11 of the 14 years. National incidence ranged from 4 to 62/million in 2003-2006 and decreased to 3/million in 2016. The age specific incidence ranged from 1 to 364/million population and was highest among children aged < 1 year. Conclusion Kenya has made progress towards measles elimination. However, this progress remains at risk and the recent declines in MCV1 coverage and the low uptake in MCV2 could reverse these gains.
The veterinarian is daily faced with the challenge of diagnosing several disease conditions in different animals. Quantifying cortisol levels has been used in the evaluation of anxiety and distress initiated by infectious and noninfectious disease conditions, mismanagement, transportation, adverse environmental temperature and surgical operations. The hormone-cortisol has been implicated in several immunologic and metabolic processes and can thus serve as a marker to monitor animal welfare. Several factors affect the specific test to be carried out and which sample is to be used. Recently, RIA has been identified as the gold standard for determination of cortisol levels. However it also has its own short comings hence the need to utilize other assay techniques such as ELISA, fluorescence techniques and chemical assays which are more common in our environment. There is also prospect for the analysis of cortisol using non-invasive samples such finger nails as well as ear wax for enhanced test results.
Introduction: Tuberculosis (TB) is a chronic infectious disease that is preventable and curable, yet a major cause of childhood morbidity and mortality. Tuberculosis prevalence and mortality are under-estimated in many high burden countries. Directly Observed Treatment Short course (DOTS) enhances treatment outcome with an overall reduction in morbidity and development of multidrug resistant TB. Objective: To determine the pattern and outcome of childhood tuberculosis managed at the DOTS clinic in Gusau, Nigeria. Methodology: A retrospective study of children managed for TB at the DOTS clinic over a 30
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