Medicines used for prevention and treatment of infection particularly bacterial infections are referred to as an antibiotic. Antibiotic is administered after surgery to kill potential infectious agents, while it is been prescribe after the manifestation of clinical sign and symptoms as well as laboratory diagnosis. Antibiotic is administered to inactivate bacteria responsible for food poisoning, wounds sepsis, respiratory tract infection, sexually transmitted infection, gastrointestinal tract infection, urinary tract infection etc. However, under certain condition bacteria developed a mechanism(s) that inactivate the bacteriostatic or bactericidal effects of the antibiotic and hence antibiotic resistance occurred. Consequently, prolong hospitalization and treatment, increase medical bill and mortality become widespread. Health care awareness, personal hygiene, agricultural products, food and industrial practices, the proliferation of substandard drugs, self-medication are some of the causes of antibiotic resistance in developing countries.
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