Summary:The present study was designed to determine the changes in the levels of serum total sialic acid and total protein, albumin/globulin ratio in naturally infected cattle with tropical theileriosis for a better understanding of the pathogenesis of tropical theileriosis. Eight cattle heavily infected (50-70% parasitamia) with Theileria annulata had significantly lower serum sialic acid, total protein, albumin and globulin levels and albumin-globulin ratios than uninfected eight control cattle. Levels of serum sialic acids were found to be 133.87±0.77 mg/dl and 194.12±3.91 mg/dl in cattle with theileriosis and healthy animals respectively. These values between two groups found to be significant (p<0.001). Levels of serum total protein were found to be 5.70 ± 0.17 g/dl and 7.00 ± 0.14 g/dl in cattle with theileriosis and healthy animals respectively. These values between two groups found to be statistically significant (p<0.001). Levels of serum albumin were found to be 2.16 ± 0.04 g/dl and 3.02 ± 0.04 g/dl in cattle with theileriosis and healthy animals respectively. These values between two groups found to be statistically significant (p<0.00). Levels of serum globulin were found to be 3.53 ± 0.15 g/dl and 3.97 ± 0.12 g/dl in cattle with theileriosis and healthy animals respectively. These values between two groups found to be statistically significant (p<0.05). Albumin-globulin ratio in serum were found to be 0.61 ± 0.02 and 0.76 ± 0.02 in cattle with theileriosis and healthy animals respectively. These values between two groups found to be statistically significant (p<0.002). These findings suggest that levels of serum proteins are usually decreased significantly in Tropical theileriosis, which may be the result of liver damage. In paralel to decreased serum proteins, sialisation of proteins in tropical theileriosis may be the result of decreased glycoproteins during the disease process. These results may be useful to evaluate the prognosis and treatment of the disease with the other laboratory findings in clinic.Key words: Sialic acid, total protein, albumin:globulin ratio, cattle, Theileria annulata Theileria annulata ile yüksek oranda enfekte sığırlarda azalan serum sialik asit, albumin-globulin oranı ve toplam protein düzeyleri Özet: Çalışmada, sığırlarda tropikal theileriosis'in patogenezis yönünden daha iyi anlaşılabilmesi için serum sialik asit, toplam protein, albumin ve globulin düzeyleri ile albumin-globulin oranları araştırılmıştır. Enfekte olmayan (kontrol) sekiz sığır ile karşılaştırıldığında, Theileria annulata ile yüksek oranda enfekte (%50-70 parazitemi) olan sekiz hasta sığırda serum sialik asit, toplam protein, albumin ve globulin düzeyleri ile albumin-globulin oranlarının önemli derecede düştüğü belirlenmiştir. Serum sialik asit ortalama değerleri sağlıklı sığırlarda 194.12 ± 3.91 mg/dl, hasta sığırlarda ise 133.87 ± 0.77 mg/dl olarak tespit edilmiş, gruplar arası farklılık önemli bulunmuştur (p<0.001). Serum toplam protein ortalama değerleri sağlıklı olanlarda 7.00 ± 0.14 g/dl, hastalar...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.