This research aims to determine the effectiveness of the antibacterial soursop leaf extract (Annona muricata L.). The method used is the agar diffusion method. The leaves were extracted by maceration method, using ethanol as a solvent. The soursop leaf extract obtained was then diluted using ethanol 96% at a concentration of 20%, 40%,60%, 80%. Positive control using clindamycin and negative controls using sterile aquadest. The research model used in this study is an experimental research model In Vitro of type. The results showed that soursop leaf extract had antibacterial effectiveness against Propionibacterium acnes with an average inhibition zone diameter of 9,7 mm; 13,7 mm; 15,7 mm; 16,3 mm; positive control (clindamysin) 21,0 mm; and negative control (aquadest) have no value tobe able to inhibit bacterial growth.
Management information systems are urgently needed by hospital pharmacy installations to maintain the quality of the hospital, protect patient safety and support fast and precise decision making. The application of management information systems in the pharmaceutical installation of the Royal Prima Medan Hospital has been running. The pharmaceutical installation system that has been implemented is evaluating, repairing and improving to keep up with the times. The purpose of this study was to determine the effect of system quality, information quality, service quality on the use of pharmaceutical management information systems at Royal Prima Medan Hospital and the relationship between significant variables. This type of research is a mixed method with a sequential explanatory research strategy. This study uses the DeLone and Mclean information system success model. The research was conducted at the Royal Prima Medan Hospital with the research subjects being pharmaceutical officers at the Royal Prima Medan Hospital. Data analysis was performed by multiple linear regression analysis. The number of respondents used in this study were 30 respondents with the characteristics of all respondents being female (100%) and aged 25-29 years (43.33%). Based on the results of the T test, it can be concluded that system quality, information quality and service quality have no effect on system use. Simultaneously, system quality, information quality and service quality do not have a significant effect on the use of management information systems simultaneously. Keywords: Evaluation, Pharmaceutical Information Management System, D & M is Success Model, Royal Prima Medan Hospital.
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