Context:Stachys guyoniana Noë ex. Batt. and Mentha aquatica L. are two Algerian Lamiaceae used in folk medicine.Objective: To investigate their antioxidant, anticholinesterase and antibacterial activities.Material and methods:n-Butanol (BESG), ethyl acetate (EESG) and chloroform (CESG) extracts of S. guyoniana and methanol (MEMA) and chloroform (CEMA) aerial part extracts of M. aquatica and methanol (MERMA) and acetone (AERMA) roots extracts of M. aquatica were evaluated for their antioxidant activity by the β-carotene-linoleic acid, DPPH• and ABTS•+ scavenging, CUPRAC and metal chelating assays. The anticholinesterase activity was tested against AChE and BChE. The antibacterial activity was assessed by MICs determination against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella heidelberg, Klebsiella pneumoniae, Enterobacter aerogenes and Morganella morganii strains.Results: In the β-carotene test, the CESG (IC50: 2.3 ± 1.27 μg/mL) exhibited the highest activity. The BESG was the best scavenger of DPPH• (IC50: 2.91 ± 0.14 μg/mL). In the ABTS test, AERMA was the most active (IC50: 4.21 ± 0.28 μg/mL). However, with the CUPRAC, the BESG exhibited the best activity (A0.50: 0.15 ± 0.05 μg/mL) and was active in metal chelating assay with 48% inhibition at 100 μg/mL. The BESG was the best AChE inhibitor (IC50: 5.78 ± 0.01 μg/mL) however, the AERMA showed the highest BChE inhibitory activity (IC50: 19.23 ± 1.42 μg/mL). The tested extracts exhibited a good antibacterial activity.Conclusion: This study demonstrated good antioxidant, anticholinesterase and antibacterial potential of S. guyoniana and M. aquatica, which fits in well with their use in folk medicine.
Herein we report the green synthesis of silver nanoparticles (EcAgNPs) from water fraction (Ecs), obtained from methanol extract of Eucalyptus camaldulensis at room conditions. UV-vis, HR-TEM and SEM-EDS devices were used to characterize the EcAgNPs. The UV-visible spectrum of EcAgNPs showed surface plasmon resonance peak at 420 nm. HR-TEM images showed that the EcAgNPs were spherical with a diameter in the range 3.7-29.6 nm. Ag + ions were reduced to Ag o by phytochemicals in the without adding external reducing agent. The presence of biomolecules in the Ecs was investigated by UPLC-MS/MS that detected gallic acid (20.26±0.10 ppb) and quercetin (12.4±0.08 ppb) as major constituents. The antimicrobial activities of Ecs and synthesized EcAgNPs were tested on Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus strains and Candida albicans yeast. Ecs exhibited antimicrobial activity as
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