The rigid long-short-pile composite foundation has been increasingly used as an effective and low-cost reinforcement method. The pile-soil interaction in this foundation type is more complicated than that in the equal-length pile composite foundation. In this study, several physical model tests were conducted to investigate the pile-soil synergistic mechanism of the rigid long-short-pile composite foundation. A comparative analysis was conducted of the static load test data of single-pile and long-short pile composite foundations to assess the load-bearing characteristics and stiffness evolution of the composite foundation and pile-soil unit. The result indicated a positive correlation between the pile length and the overall bearing capacity of the single-pile composite foundation. The overall stiffness of the four-pile composite foundation was lower than that of the single-pile composite foundation due to an increase in the areas of the soil stress and the pull-down effect caused by multiple piles. The long pile exerted a greater influence on the overall settlement than the short pile. In addition, the correction coefficients were obtained to determine the pile-soil stiffness of the four-pile composite foundation based on that of the single-pile composite foundation, providing a theoretical reference for the optimal design of composite foundations.
Objective: To assess the practical utility of pleural fluid carbonic anhydrase XII (CAXII) quantification for differential diagnosis of effusions. Materials and Methods: Fluid was collected prospectively from fifty patients presenting with lymphocytic pleural effusions for investigation and CAXII was quantified by ELISA. Results: Pleural fluid CAXII concentrations were significantly higher in lung cancer patients (n=30) than in tuberculous controls (n=20). The sensitivity and specificity of this biomarker were 60%and 75%, respectively. CAXII measurement was not inferior to cytological examination in the diagnosis and exclusion of pleural effusions from lung cancer patitents (sensitivity 60% vs. 57%; specificity 75% vs. 100%; positive predictive value 77%; negative predictive value 54%). In patients with negative cytology, it offered a sensitivity of 54%. Conclusions: Pleural fluid CAXII is elevated in pleural effusions from lung cancer patients. Measurement of CAXII may be used in the future as a valuable adjunct to cytology in the diagnostic assessment of patients with pleural effusions related to lung cancer, especially when cytological examination is inconclusive.
Laboratory model testing of single pile and superlong pile groups in saturated silty sand was conducted to investigate the response and bearing behavior of superlong pile groups with a high or low cap under vertical loads. The load transfer mechanism and bearing behavior of the pile shaft were discussed in detail. The load-settlement curve of the loaded superlong pile groups belongs to the type of gradual descent in silty sand. The transferred load decreased along the pile length during loading, but the gradients differed in different positions of the superlong pile group foundation with a high or low cap. The maximum shaft friction of the superlong pile groups with a high and low cap is about 2.5 times and 1.8 times, respectively, than that of the single pile. In addition, the tip resistance of the piles in the pile group foundation is about 2–3.5 times that of the single pile. The friction resistance of the superlong pile group foundation with a low cap was slightly larger than that of the high cap in the entire pile length, and two peaks and one peak, respectively, were observed. Under the ultimate load, the pile-soil maximum relative displacement of the friction on the pile side in the silty sand stratum was about 3% of the pile diameter. Under the ultimate load, the load sharing ratio of the pile side resistance of the two types of pile group foundations was about 60% of the total load. The load sharing ratios at the pile tip of the superlong pile groups with high and low caps are 40% and 33%. Furthermore, equations were proposed to determine the axial capacity of the superlong pile group based on the single pile bearing capacity and were applied to analyze the test pile. The calculated ultimate bearing capacity was similar to the measured value, with a maximum error of only 4.88%, thus validating the proposed method.
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