Topotactic anion exchange has been developed to tune the composition and band gap energies of cesium lead halide (CsPbX3) perovskite nanocrystals (NCs). However, current anion exchange methods either require harsh conditions or take a long time to realize substantial substitution. Here, we present a method to modulate the composition of colloidal CsPbBr3 NCs through ultrasonication-assisted anion exchange with CsX (X = Cl, I) solution. Efficient anion exchange of CsPbBr3 NCs with Cl− or I− is realized with substitution ratio up to 93% and preservation of the pristine shape and structure of CsPbBr3 NCs. This anion exchange results in tunable emission, covering the whole visible spectral range, with relatively high photoluminescence quantum yield, narrow emission bandwidths, and good stability. This work provides a facile and efficient way to engineer the properties of halide perovskite NCs and has great potential for large-scale production of compositionally diverse perovskite NCs.Electronic supplementary materialThe online version of this article (10.1186/s11671-018-2592-4) contains supplementary material, which is available to authorized users.
RMP has been shown to function in the transcription regulation through association with RNA polymerase (RNAP) II subunit RPB5. It also has been shown to be required for the proliferation of hepatocellular carcinoma (HCC) cells with an antiapoptotic property. In this article, we further demonstrate that RMP displays distinct features in HCC cells compared with normal hepatic cells. RMP expression is remarkably increased in various cancer cell lines including HCC cells when compared with normal cells. Depletion of RMP could inhibit the proliferation of HCC cells, but not the normal hepatic cells. RMP significantly prevented apoptosis of HCC cells in SMMC-7721 and HepG2, but had little effect on apoptosis in the normal hepatic cells. The mechanisms of RMP's distinct features rely on different responsive expressions of apoptosis factors induced by RMP in HCC and hepatic cells. Either overexpression or depletion of RMP significantly affected the expression of apoptosis factors in HCC cells. However, normal hepatic cells showed a tendency to resist RMP for the regulation of apoptosis. In the clinical samples, the increased expression of RMP in HCCs was also observed when compared with the matched non-tumor tissues from 30 HCC patients. The different expression levels of and distinct responses to RMP between HCC and hepatic cells suggest that RMP might serve as not only a biomarker for the diagnosis of HCC, but also a potential target for the HCC therapy.
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