Doping analysis with a fast‐turnaround‐time reporting of 24/48 h is a “traditional” requirement for major competitions such as the Olympic Games, which require tremendously increased allocation of resources, especially during the COVID‐19 pandemic. The “Closed‐Loop” concept and operation mode established by the Beijing Organizing Committee for the 2022 Olympic and Paralympic Winter Games (BOCOG) provided a relatively isolated environment to non‐Games‐related civilians. To maintain this system, more than 200 persons were included as supporting crew of the laboratory with massive logistic resources allocated. The National Anti‐Doping Laboratory in Beijing carried out the analysis mission of the Beijing 2022 Olympic and Paralympic Winter Games. During the Winter Olympics, 3165 samples were analyzed, whereas during the Paralympics, 679 samples were analyzed. The workforce accomplishing this work was composed of 36 domestic analysts, 20 international experts from other World Anti‐Doping Agency‐accredited laboratories, 61 university students with suitable majors, and 12 on‐site instrumental engineers. This article summarizes the achievements from the laboratory's preparation phase; in‐Game operational details such as instruments, methods, workforces, and facility; and the Quality Assurance measures to maintain the integrity and correctness of results reported to the Result Management Authority, with the effect of the pandemic and “Closed‐Loop” situation during the whole process highlighted.
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