Molecular hydrogen is an effective antioxidant. Numerous studies have demonstrated the therapeutic effects of hydrogen in the treatment of various human diseases. The possibility of using hydrogen in the treatment of cancer was first discovered in 1975, and in recent studies, researchers have reported numerous positive effects of hydrogen in cancer therapy, including: 1) the alleviation of complications caused by chemotherapy; 2) a reduction of complications caused by radiotherapy; 3) delays in the progression of cancer; and 4) enhanced efficacy of conventional therapy when used in combination with hydrogen. This article reviews the research progress in the use of hydrogen in the treatment of cancer, and proposes future directions for research in this field.
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