Colorectal adenocarcinoma originating in intestinal glandular structures is * Corresponding authors Email addresses: k.sirinukunwattana@warwick.ac.uk (Korsuk Sirinukunwattana), n.m.rajpoot@warwick.ac.uk (Nasir M. Rajpoot) Preprint submitted to Medical Image AnalysisAugust 30, 2016the most common form of colon cancer. In clinical practice, the morphology of intestinal glands, including architectural appearance and glandular formation, is used by pathologists to inform prognosis and plan the treatment of individual patients. However, achieving good inter-observer as well as intra-observer reproducibility of cancer grading is still a major challenge in modern pathology. An automated approach which quantifies the morphology of glands is a solution to the problem. This paper provides an overview to the Gland Segmentation in Colon Histology Images Challenge Contest (GlaS) held at MICCAI'2015. Details of the challenge, including organization, dataset and evaluation criteria, are presented, along with the method descriptions and evaluation results from the top performing methods.

Although previous researchers have paid significant attention to the effect of feedback on employee behavioral outcomes, few have specifically examined the influence of developmental feedback on employee job performance. In this study we examined the influences of intrinsic motivation and social exchange on the relationship between developmental feedback and job performance. Participants were 202 supervisor-subordinate dyads from 12 enterprises in China. We found that developmental feedback had a significant positive effect on both intrinsic motivation and job performance. In addition, intrinsic motivation had a significant positive relationship with job performance but it also had a partial mediating effect on the relationship between developmental feedback and job performance. Managerial implications and directions for further research are discussed.

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A method for efficiently catalyzing the oxygen evolution reaction (OER) represents a top priority for water electrolysis due to its multistep electron transfer pathway and sluggish kinetics. The OER activity can be promoted by generating high valence transition-metal species in the electrocatalysts. In the present work, a versatile anion–cation double doped Co3O4 (Se/Ni-Co3O4) microtube architecture is innovatively fabricated as an OER electrocatalyst, by combining reliable and template-free solvothermal strategy and calcination treatment. The obtained Se/Ni-Co3O4 possesses some desirable properties for OER including an attractive mesoporous structure, abundant exposed active species associated with surface oxygen vacancies, and fast charge transfer rate. By precisely exploring the redox reaction behavior, it is found that the effective Se and Ni double doping could readily promote the generation of active Co­(IV) species. Consequently, the obtained Se/Ni-Co3O4 electrocatalyst affords a very good OER electrocatalytic activity with an onset potential of 1.47 V, small Tafel slope (62.9 mV dec–1), and excellent durability in alkaline solution, which is even superior to that obtained in the benchmark RuO2. The novel strategy introduced in this research may open a new opportunity for the rational design of highly efficient Co3O4-based OER electrocatalysts.

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