A high eradication rate can be achieved with one-week OAC or OFC triple therapy. Thus, one-week triple therapies with OAC and OFC are recommended for Chinese patients with duodenal ulcers and chronic gastritis.

An efficient olefination protocol for the oxidative dehydrogenation of phenols and acrylates has been achieved using a palladium catalyst and O2 as the sole oxidant. This reaction exhibits high regio- and stereo-selectivity (E-isomers) with moderate to excellent isolated yields and a wide substrate scope (32 examples) including ethyl vinyl ketone and endofolliculina.

Actions of ET-1 on collagen metabolism of HSCs may depend on the transportation of inward whole-cell calcium.

An approach to preparing enynyl-aryl ethers from phenols and phenylacetylenes is described. This method without extra ligands, overcoming the favored Glaser-Hay dimerization of alkyne, features a wide substrate scope (38 examples including endofolliculina and indole) and the merits of high atom and step economy, good regioand stereoselectivity (Z-isomers major) in moderate to good isolated yields. Mechanistic studies show that the reaction is enabled by distinctive copper/ iodide tandem catalysis.

Benzimidazole-fused dihydrobenzoxazoles are an important class of complex heterocycles containing both nitrogen and oxygen as building blocks for materials and pharmaceuticals. Traditional synthetic method for the skeleton lacks of step economy. This article describes the tandem cyclization of 1H-benzimidazole and 2-bromophenol catalyzed by copper(II) via N-arylation/sp 2 C−H activation/C−O bond cyclization to construct benzimidazole-fused dihydrobenzoxazoles in one-pot. The reaction was carried out under an air atmosphere with simple reactive conditions and easy handling. In addition, other benzimidazole derivatives, as well as 2-iodophenol and 2-hydroxybenzeneboronic acid, are also suitable for this reaction. This transformation provides a convenient method to synthesize a series of benzimidazole-fused dihydrobenzoxazoles.