Although it is illegal to use tigecycline and carbapenems to treat bacterial infections in animals, we can still isolate bacteria containing both mobile resistance genes from animals, and
tet
(X) is currently an essential factor in degrading tigecycline. Here, we characterized two multidrug-resistant
Acinetobacter
sp. strains that contained vital resistance genes, such as
sul2
, a
bla
OXA-164
-like gene,
floR
,
tetM
, and multiple novel
tet
(X3) variants with different tandem structures.
Here, we report the widespread and complex genetic environments of
fosA
-like genes in animal-derived strains in China. The
fosA7.5
gene was identified in this study and was found to confer resistance to fosfomycin.
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