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Ancylostomiasis is a fairly common small bowel parasite disease identified by capsule endoscopy (CE) for which a computer-aided clinical detection method has not been established. We sought to develop an artificial intelligence system with a convolutional neural network (CNN) to automatically detect hookworms in CE images. We trained a deep CNN system based on a YOLO-V4 (You Look Only Once-Version4) detector using 11236 CE images of hookworms. We assessed its performance by calculating the area under the receiver operating characteristic curve and its sensitivity, specificity, and accuracy using an independent test set of 10,529 small-bowel images including 531 images of hookworms. The trained CNN system required 403 seconds to evaluate 10,529 test images. The area under the curve for the detection of hookworms was 0.972 (95% confidence interval (CI), 0.967-0.978). The sensitivity, specificity, and accuracy of the CNN system were 92.2%, 91.1%, and 91.2%, respectively, at a probability score cut-off of 0.485. We developed and validated a CNN-based system for detecting hookworms in CE images. By combining this high-accuracy, high-speed, and oversight-preventing system with other CNN systems, we hope it will become an important supplement for detecting intestinal abnormalities in CE images. This trial is registered with ChiCTR2000034546 (a clinical research of artificial-intelligence-aided diagnosis for hookworms in small intestine by capsule endoscope images).

This paper will introduce the design of wideband frequency agility synthesizer based on method of Simulate direct frequency synthesis, the full-phase coherence Modulation and Filter bandwidth control are applied in this synthesizer as designed .The main factors and solutions of the effect of the frequency switching time are analyzed and the frequency change time of the system is tested. The result shows that the frequency switching time between any two frequencies is less than 0.8 μs on the full band.

Global green energy development by many technological breakthroughs, so that the new composite materials modified and designed, so that new energy has a new look, this study to improve people’s high-pressure hydrogen storage of hydrogen energy technology hazards and hidden worries, so design and improve the local low-pressure hydrogen storage combined with secondary building wall design, and sustainable environmental thinking, The use of waste ceramic reuse technology, combined with low-pressure hydrogen bottle design to form a new composite material structure, and the best parameters to solve waterproof non-sintered ceramic clad metal material research, and OM, salt spray, perspective X-RAY observation with metal now ceramic anti-corrosion permeability, the future use of geotechnical engineering, building diversification. More so that hydrogen in non-high pressure, more in people’s life circle and local hydrogen storage and PC use. Thank partially support by the MOST 108-2221-E-343-001.

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In order to avoid contaminations and spread of diseases in the use of needles, hospitals adapted disposable policy after one single used. Needles should be used only once and must be disposed of for recycling to avoid infections and spread of diseases. Also to avoid any poking accidents to the medical staffs and recycling personnel in the process of collection, it was accustom to put the needle head back to the needle case, but because the hole of the needle case is small, medical personnel could be by accident or carelessness poke the needle to his or her own hand. This design proposes an innovative collection box for the needle of syringe recycle under safety and management consideration. It can effectively recycle needles in real time and record the time of using needles. It can avoid people repeated use of drugs at home that is a mentally disabled. It is not only simple in structure and low costs, but also easy to operation. It can avoid puncturing the medical personnel and personnel who recycle medical waste. This collection box is composed of a box body and a box cover. On the box cover, it contains one or more needle recycle holes. The needle can be plugged on the needle recycle hole. And the hole has a large circular portion of the fixed ring. Furthermore, the top end with several Bumps structure called Fixing pin fork can restrict the needle to avoid detachment on the inner side of in the upper diameter hole. Therefore, plugging the needle into the box cover and using Fixing pin fork at in the upper diameter hole can separate the needle and syringe. After that, the used needle and syringe can be stored inside the collection box. In this design, it demonstrates a simple structure with a low production cost. Moreover, it is very convenient for people usage.