During high-temperature energy-based therapies such as radiofrequency ablation (RFA) the target tissue reaches temperatures around 100ºC, which causes tissue dehydration by water vaporization. In order to be as realistic as possible, RFA theoretical models should include the formulation of these phenomena. There are currently two fixed mesh methods of modeling the electrical and thermal effects produced by water vaporization: the enthalpy method and the water fraction method. Our objective was to compare both methods, especially to assess the thermal and electrical performance in terms of electrical impedance progress during heating, distributions of temperature, and temperature progress at some specific locations. The results showed the performance of both methods to be qualitatively analogous, with similar impedance progress, temperature distributions and temperature progress. They were hence equally able to mimic the thermal and electrical performance in a pulsed protocol, i.e. during the period without applying RF power. The main difference between the methods was the time at which impedance started to rise. All these findings suggest that the two methods offer equivalent results in RFA modeling. However, since the enthalpy method has one less problem to be solved (dynamic volume fraction of liquid water in the tissue) it is less complex, has a lower computational cost and therefore seems to be more suitable for modeling RFA with dry or internally cooled electrodes, i.e. those in which there is no interstitial saline infusion. However, the water fraction method would be more appropriate in the case of RFA with externally irrigated electrodes.
Abstract. This paper deals with the problem of dynamic behavior of thin geometrically imperfect shell structures made of functionally gradient material (FGM) with time dependent parameters. Hybrid asymptotic approach is used to obtain an approximate analytical solution of the problem. The material properties are graded in the thickness direction according to the given law distribution and initial conditions. The non-linear strain-displacement relationships based upon the von Karman theory for moderately large normal deflections. Discussed problem leads to a singular non-linear second order non homogeneous differential equation with variable in time coefficients. An analytical solution by hybrid perturbation-WKB-Galerkin (P-WKB-G) method in some parameters of structure is compared with direct numerical integration results of initial equation of the problem.8654
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