The great problem of rabbits breeding today is coccidiosis. An agent of the disease spreads not only through ill animals and is preserved well in the external environment. Oocysts of coccidia live in cells for a long time, so even temporal vacation of an accommodation between placing of rabbits doesn’t prevent infection. It was experimentally proved, that there is a very limited spectrum of means that are coccidiostatics. For preventing and controlling rabbits’ eimeriosis, coccidiostatic means were tested. It is very difficult to annihilate coccidia in vivo and in vitro because of peculiarities of their construction. The aim of the first experiment was to determine the influence of an acidifier Cronocyde L and its components on oocysts of coccidia that allows to determine an optimal composition and concentration of the preparation. At conducting the research, there was used the flotation method of Fulleborn and McMaster one for calculating oocysts. The aim of the second experiment was to determine the influence of the acidifier Cronocyde L standard and Cronocyde L concentrate (1 ml/1l of water) on the intensity of the living mass increment in rabbits. For that there were used clinical, hematological, zootechnical and microscopic methods. Optimal results in the experiment were obtained at using Cronocyde L concentrate and Cronocyde L standard in concentration 0,1 %: maximal growth and health status of rabbits, biochemical indices of blood serum were within the physiological norm. It testifies to the effectiveness of this preparation at eimeriosis of rabbits and to harmlessness for them. The studies, realized under laboratory conditions, prove the effectiveness of the offered means.
Coccidiosis (eimeriosis) is an animal disease that is widespread in the world and causes significant economic damage to the agriculture. Due to the technological features of keeping rabbits in cages, they are massively susceptible to this disease. Studies show, that the infection of rabbits with coccidiosis in different areas varies from 30 to 100 %. The death of infested young rabbits reaches 80-100 %. Sick animals lag behind in growth and lose from 12 to 30 % of their weight. Adult animals are less sensitive to coccidiosis, but they are carriers and sources of the eimeric infection [2, p. 46-47; 4]. Thus, the protection from coccidiosis is an important area of veterinary medicine. In connection with the rapid adaptation of the simplest Eimeria to the drugs used, it is necessary to constantly search for new treatment regimens and to replace them reasonably [5, p. 159-162; 6]. The aim of this research is to determine the time of occurrence of resistance of the coccidiosis causative agents to the acidifier "Kronocide-L" as well as to develop recommendations on prevention the reduction of treatment effectiveness. Scientific novelty of the workthe relationship between the drugs used for the treatment of rearing females and underperformance of these drugs in the treatment of young animals was determined, as well as schemes and recommendations to prevent this phenomenon were developed.
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