We demonstrated that NBL was significantly shorter and BPD/NBL was significantly greater in the Japanese population than those in the white and black populations.

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Our study suggested that STIC used by general obstetricians to check normality of fetal cardiac structures at 17-21 weeks' gestation has marginal clinical effectiveness when compared to 2D scanning by a fetal echocardiologist, and should need some improvement before it can be used as a tool to expand a fetal cardiac screening program.

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