Salivary gland tumors represent 2% -6.5% of all head and neck tumors. Since salivary gland tumors have various clinical features and histological types, it is often difficult to diagnose and treat them. The aim of this study was to conduct a retrospective clinical-statistical analysis of 37 minor salivary gland tumors (MSGTs) treated in the Department of Oral Surgery at Nihon University School of Dentistry at Matsudo over a 16-year period. The frequencies and distributions of sex, age, occurrence site, preoperative examination (fine needle cytology and/or biopsy), treatment, and prognosis of the tumors were analyzed and compared with previous reports. The average age at diagnosis was 58.1 years (range 22 -91 years). The peak occurrence of tumors was in the sixties (10 cases, 27.0%), followed by the forties (8 cases, 21.6%) and the seventies (7 cases, 18.9%). The average age of patients with benign tumors was 56.8 years (range 22 -91 years). For malignant tumors, the average age was 61.7 years (range 42 -81 years). The male-female ratio was 1:2.1 for all minor salivary gland tumors, 1:2.4 for benign tumors, and 1.5:1 for malignant tumors. There were 27 (73.0%) benign and 10 (27.0%) malignant tumors. Pleomorphic adenoma (PA) was the most common tumor (24 (64.9%) cases). Most salivary gland tumors originated from the palate (21 cases, 56.8%); the second most common site was the buccal mucosa (14 cases, 37.8%). For most patients, an intraoral mass was the primary presentation, and the second most common symptom was swelling. Surgical treatment was performed for all cases, both benign and malignant tumors. There was one case of local recurrence of PA, as well as one of multiple lung metastases after surgery for adenoid cystic carcinoma. Diagnosis and treatment of MSGTs are often delayed because the pa-How to cite this paper:
the most common type being oral squamous cell carcinoma (OSCC). OSCC may arise in any part of the oral cavity, including the tongue, gingiva, hard palate, buccal mucosa, and floor of the mouth. The most frequent location of occurrence is the tongue, followed by the lower gingiva and the floor of the mouth (1). Important clinical factors in the evaluation of tumor progression are primary tumor size, cervical lymph node metastasis, and distant metastasis. Therefore, the tumor/node/metastasis (TNM) classification of the Union for International Cancer Control (UICC) is used to determine treatment regimens for oral cancer. Among them, cervical lymph node metastasis is one of the important factors affecting the prognosis of patients. OSCC often metastasizes to the cervical lymph nodes (CLN). CLN are removed by cervical dissection, and the levels, number of metastases, size, and extracapsular nodule infiltration of lymph nodes are recorded as histopathological findings (2). However, evaluation by immunohistochemical staining has not been performed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.