To introduce a phosphorylcholine (PC) moiety into segmented polyurethane, which has been widely used as an elastic material, the synthesis of a novel diol monomer containing a PC unit was performed. PC-containing polyurethanes were then prepared by polyaddition of the diol monomer and poly(carbonate diol) with 4,4 0 -diphenylmethane diisocyanate. The obtained polyurethanes were soluble in aprotic polar solvents, such as N,N-dimethylacetamide, N,N-dimethylformamide (DMF) and dimethyl sulfoxide, but were insoluble in water and alcohol. According to thermal analysis and the stress-strain measurements, the polyurethane films exhibited thermal stability up to 250 1C and elastic properties with high tensile strength. In addition, it was confirmed from the results of the protein adsorption experiments that the PC-containing polyurethane films efficiently reduced protein adsorption to the surface. Japan (SPSJ) All rights reserved 0032-3896/13 www.nature.com/pj
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.