No abstract

BackgroundVitamin D is essential for calcium metabolism, Vitamin D deficiency can precipitate osteoporosis, cause muscle weakness and increase the risk of fracture. The aim of this study was to assess the prevalence of vitamin D inadequacy among non-supplemented postmenopausal women with osteoporosis and fragility fractures of the hip or vertebrae in Taiwan.MethodsThis multi-center, cross-sectional, observational study analyzed the vitamin D inadequacy [defined as 25(OH) D level less than 30 ng/mL] in Taiwanese postmenopausal osteoporotic patients who suffered from a low trauma, non-pathological fragility hip or vertebral fracture that received post-fracture medical care when admitted to hospital or at an outpatient clinic.ResultsA total of 199 patients were enrolled at 8 medical centers in Taiwan; 194 patients met the study criteria with 113 (58.2%) and 81 (41.8%) patients diagnosed with hip and vertebral fracture, respectively. The mean serum 25(OH) D level was 21.1 ± 9.3 ng/mL, resulting in a prevalence of vitamin D inadequacy of 86.6% of the patients.ConclusionsHigh prevalence of vitamin D inadequacy across all age groups was found among non-supplemented women with osteoporosis and fragility hip or vertebral fracture in Taiwan.

No abstract

No abstract

Level III, comparative study.

The capacity of low-intensity pulsed ultrasound to accelerate the integration of grafted tendon-within-bone tunnel was evaluated. The extensor digitorum longus tendons of 20 New Zealand white rabbits were transplanted into bone tunnels in both proximal tibias. One side was chosen randomly to receive low-intensity pulsed ultrasound. The other side served as control. Six rabbits each were sacrificed at 2 and 3 weeks postoperatively for biomechanical testing, and 2 rabbits each were sacrificed at 1, 3, 6, and 12 weeks postoperatively for histological study. At 2 weeks postoperatively, the mean maximal tensile strength in the ultrasound-treated group (30.676 N) was significantly stronger (P<.05) than the control group (17.924 N). There was no significant difference of the maximal tensile strength (33.674 vs 33.340 N; P=.753) between the ultrasound-treated and control groups at 3 weeks postoperatively. In the ultrasound-treated group, the histological study revealed the interface filled with denser granulation tissue and diffuse perpendicular anchored fibers in the 1- and 3-week specimens, and interface new bone formation in the 6- and 12-week specimens. The biomechanical and histological studies demonstrated that the low-intensity pulsed ultrasound enhanced the healing of grafted tendon-to-bone tunnel in the early stages. Our findings indicate that low-intensity pulsed ultrasound is a potentially promising mechanical tool to accelerate early tendon healing to bone tunnel.

Gunshot wounds involving major joints can be lethal as a result of the disruption to major neurovascular tracts. We report on a high-energy ballistic injury resulting in a comminuted femoral neck fracture in an elderly patient with a surgical delay exceeding 20 h. The patient underwent bipolar hemiarthroplasty and led a functional, satisfactory life after surgery. Lead intoxication was also identified, and the blood lead concentration was almost two times the positive diagnostic value (25 μg/dL). The rebound in lead concentration suggested delayed lead toxicity. The patient did not have symptoms of plumbism at the last follow-up 4 years after the injury.