NEAT1 regulates HMGA1 via miR-214-3p to regulate Wnt/β-catenin pathway, thus promotes the growth, migration and invasion of HEC-1A cells.

Livestock overgrazing influences both microbial communities and nutrient cycling in terrestrial ecosystems. However, the role of overgrazing in regulating the relationship between soil biodiversity and nitrogen availability remains largely unexplored. We performed long‐term grazing exclusion experiments across eight sites along precipitation gradient covering three major types of grassland in northern China to compare the linkage between soil microbial diversity and N availability in overgrazed versus non‐grazed conditions. We found a significantly positive association between fungal diversity and soil available N in non‐grazed grasslands. However, the positive association was absent in overgrazed environments. Bacterial diversity is not related to soil available N in either non‐grazed or overgrazed grasslands. Moreover, in bacterial community, we found a positive link between the relative abundance of Actinobacteria with soil available N in non‐grazed, but not overgrazed, grasslands. Instead we found the links between relative abundance of Bacteroidetes and Acidobacteria with soil available N in overgrazed grasslands, but not non‐grazed, grasslands. Synthesis. Our work provides evidence that the relationships between microbial diversity and ecosystem functions are context‐dependent, and so microbial community diversity is likely not the major driver of soil N mineralization in overgrazed grasslands. Our study suggests that high intensity anthropogenic activities in grasslands restrains the capacity of diverse soil microbial communities to sustain ecosystem function, and more broadly the capacity of entire ecosystems to maintain important ecosystem processes such as plant production. Our study also indicates that the fundamental microbial communities associated with N availability change with differing land management strategies (e.g. livestock grazing). A free Plain Language Summary can be found within the Supporting Information of this article.

A series of MCM-22/ZSM-35 composites has been hydrothermally synthesized and characterized by XRD, SEM, particle size distribution analysis, N 2 adsorption and NH 3 -TPD techniques. Pulse and continuous flow reactions were carried out to evaluate the catalytic performances of these composites in aromatization of olefins, respectively. It was found that MCM-22/ZSM-35 composites could be rapidly crystallized at 174°C with an optimal gel composition of SiO 2 /Al 2 O 3 =25, Na 2 O/SiO 2 =0.11, HMI/ SiO 2 =0.35, and H 2 O/SiO 2 =45 (molar ratio), of which the weight ratio of ZSM-35 zeolite in the composite relied on the crystallization time. The coexistence of MCM-22 and ZSM-35 in the composite (MCM-22/ZSM-35=45/55 wt/wt) was observed to exert a notable synergistic effect on the aromatization ability for butene conversion and FCC gasoline updating, possibly due to the intergrowth of some MCM-22 and ZSM-35 layers.

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