Purpose: To evaluate the antidiarrhea and antioxidant properties of honokiol extracted from Magnoliae officinalis cortex (bark of Magnolia officinalis), an important medical material in traditional Chinese 16 % in comparison with -neostigmine control group-(59.0 % vs. 70
.1%). Compared with control (no honokiol), the activities of catalase (CAT), glutathione peroxidase (GSH-Px) and total superoxide dismutase (T-SOD) in the plasma (CAT, 7.31 vs. 13.21 U/mL; 439.6 vs. 608.9 U/m; 82.2 vs. 109.8 U/mL) and liver (CAT, 7.73 vs. 14.39 U/mg; 167.6 vs. 202.7 U/mg; 44.3 vs. 53.9 U/mg) were significantly enhanced by honokiol (p < 0.01). CAT and GSH-Px gene expressions were also significantly enhanced by honokiol (p < 0.05), compared with control (no honokiol) (CAT, 0.32 vs. 0.39; 4.49 vs. 5.80
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