A closer association has been found between the microRNA-146a rs2910164 polymorphism and the risk of head and neck carcinoma in some molecular epidemiological studies. Recently two meta-analyses were performed to explore the relationship between miRNA-146a polymorphisms and the susceptibility of squamous cell carcinoma of the head and neck (SCCHN); however, they yielded conflicting results in susceptibility regarding ethnic variations. Hence, the present study was performed to explain the relationship between the miRNA-146a rs2910164 polymorphism and the risk of SCCHN development of Chinese patients. We retrieved databases and screened eligible papers up to March 10, 2017 and then we extracted the essential data. The subgroup analyses were also performed based on the tumor site, region, and genotyping means. Crude odds ratios (OR) at 95% confidence intervals (CI) were chosen to describe the strength of the association. As a result, 6 publications were included in our study which involved 8 independent case-control studies. A significant association was found between miR-146a rs2910164 polymorphisms and the risk of SCCHN in Chinese patients according to the overall data [CC+CG vs. GG: OR = 1.13; 95%CI = 1.00–1.29; CC vs. GG: OR = 1.19; 95%CI = 1.03–1.38]. According to the subgroup analysis based on tumor site, the risk of cancer was significantly increased among laryngeal cancer (dominant model: OR = 1.76, 95%CI = 1.26~2.46, P = 0.001; homozygote model: OR = 1.83, 95%CI = 1.25~2.67, P = 0.002) and nasopharyngeal carcinoma (homozygote model: OR = 1.41, 95%CI = 1.05~1.90, P = 0.022). In summary, variant alleles of miR-146a rs2910164 alleles may have an association with the increased risk of SCCHN in Chinese patients, and these associations differed based on tumor site. Further studies including a larger sample size will be necessary to clarify these results.
The Chinese Chang’E-5 probe landed in the Mons Rümker of Oceanus Procellarum on the near side of the Moon. The lunar regolith penetrating radar (LRPR) carried by the Chang’E-5 probe allows for the determination of in situ lunar regolith dielectric properties, which are probably related to the age and chemical composition of the regolith. In this paper, we analyze the Chang’E-5 LRPR data with the frequency shift method to estimate the loss tangent of the lunar regolith within a depth of ∼2.8 m. The loss tangent of the Chang’E-5 landing site is constrained to be 0.0148 ± 0.0016, which is substantially higher than that of the typical lunar regolith. The high loss tangent is found to be characteristic of the young basalt age (∼2.0 Ga) and high TiO2+FeO content (28.21 ± 1.57%) of the Chang’E-5 landing site. Integrated analysis of results from Chang’E-3, Chang’E-4, and Chang’E-5 show that the younger is the geologic age of the mare unit, the greater is the loss tangent of the lunar regolith, and the weaker is the radar electromagnetic signal penetrating ability.
Environmentally friendly and low-cost MoS 2 /sisal fiber tubular carbon (MoS 2 /SFTC) nanohybrids have been prepared via a facile hydrothermal-anneal strategy, in which the tubular biomass carbon derived from natural sisal fibers as a conductive base. The as-prepared nanohybrids are characterized by Raman spectra, XRD, XPS, FESEM, TEM and EDS. It is shown that the sisal fiber tubular carbons with nanowrinkles and nanofolds were uniformly coated with vertical MoS 2 nanosheets on the surface. As an anode material for lithium ion batteries, the MoS 2 /SFTC nanohybrids possess an excellent cycling performance, superior rate capability and high reversible capacity. A reversible specific capacity of 437.2 mA h g -1 is maintained after 50 cycles at the current density of 50 mA g -1 . Even at a high current density of 2000 mA g -1 , the reversible specific capacity could be retained at 241.1 mA h g -1 . The superior electrochemical performance of the MoS 2 /SFTC nanohybrids can be attributed to the synergistic effects of uniform vertical MoS 2 nanosheets and conductive SFTC nanostructures.
In this work, we designed and successfully synthesized an interconnected carbon nanosheet/MoS2/polyaniline hybrid (ICN/MoS2/PANI) by combining the hydrothermal method and in situ chemical oxidative polymerization. The as-synthesized ICNs/MoS2/PANI hybrid showed a “caramel treat-like” architecture in which the sisal fiber derived ICNs were used as hosts to grow “follower-like” MoS2 nanostructures, and the PANI film was controllably grown on the surface of ICNs and MoS2. As a LIBs anode material, the ICN/MoS2/PANI electrode possesses excellent cycling performance, superior rate capability, and high reversible capacity. The reversible capacity retains 583 mA h/g after 400 cycles at a high current density of 2 A/g. The standout electrochemical performance of the ICN/MoS2/PANI electrode can be attributed to the synergistic effects of ICNs, MoS2 nanostructures, and PANI. The ICN framework can buffer the volume change of MoS2, facilitate electron transfer, and supply more lithium inset sites. The MoS2 nanostructures provide superior rate capability and reversible capacity, and the PANI coating can further buffer the volume change and facilitate electron transfer.
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