Bimetallic PtRu nanozymes exhibited enhanced multiple enzyme-like activities, and pro-oxidant and antioxidant capabilities, and have shown applications in biological detection and protection.
Metallic
nanozymes attracted broad interest because of their efficient
catalytic activities and wide applications in biological detection
and therapeutics. In this study, PtPdCu trimetallic nanoalloys (TNAs)
are prepared by chemical coreduction of Pt2+, Pd2+, and Cu2+ in an aqueous solution. The formation of PtPdCu
TNAs is characterized by scanning electron microscopy (SEM), transmission
electron microscopy (TEM), X-ray diffraction (XRD), energy-dispersive
system (EDS), and X-ray photoelectron spectroscopy (XPS). Compared
to PtPd bimetallic nanoalloys (BNAs) and commercial Pt/C, PtPdCu TNAs
have enhanced enzymelike activities, including peroxidase, oxidase
(ferroxidase), and catalase, as well as increased DPPH free radical
scavenging ability. Due to the synergistic effect between heteroatoms,
the incorporation of Cu into Pt and Pd to form trimetallic structure
not only exposes more active surfaces but also causes a change in
the electronic structure, which is beneficial to improve the enzymelike
catalytic activity. Using the ferroxidase-like and peroxidase-like
activity of PtPdCu TNAs, we demonstrate the applications of PtPdCu
TNAs in selective detection of Fe2+ in oral supplements
and evaluation of the antioxidant capacity of natural antioxidants
and tea extracts. Three natural antioxidants tannic acid (TA), gallic
acid (GA), and ascorbic acid (AA) are found to show different inhibitory
behaviors on peroxidase-like activity of PtPdCu and share the order
of antioxidant capability TA > GA > AA.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.