Despite a majority of patients having <60% TTR, there were low incidences of bleeding and stroke events in this center. There were no factors found to be associated with INR control in this study.
Ganglioneuroma (GN) is a rare benign neurogenic tumor which arises from the neural crest cells that represent the final maturation stage of neuroblasts. GN is commonly encountered in adolescent or young adult. Until now, only a few cases of intrathoracic GN were reported in pediatric patients, especially in below 10 years of age. We report here an 8-year-old boy, who first presented to primary care with symptoms of upper respiratory tract infection. Radiologic investigations revealed a giant posterior mediastinal mass extending from T4 to T9 vertebrae without evidence of vascular invasion or infiltration into adjacent structures. The patient subsequently underwent left thoracotomy and resection of mass under general anesthesia. He was discharged 3 days after operation without complication. Histopathologic examination confirmed the diagnosis of thoracic GN. Grades of the neuroblastic differentiation increase with the median age at diagnosis. Although GNs are usually benign, they can grow aggressively and cause compression to an adjacent structure. Therefore, surgical resection is the only treatment. Debulking of tumor provides an alternative solution, especially when vital structures are involved. Complete resection remains the gold standard treatment for GN. However, in cases of incomplete resection, all residual tumors require regular clinical and radiodiagnostic follow-up.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.