Gas chromatography was used to separate enantiomers of limonene on a meter packed column filled with an inert carrier with a mixed supramolecular structure of uracilmelamine applied to the surface at a 1:1 ratio. The new phase showed enantioselectivity with respect to the enantiomers of limonene in the temperature range of 40-80°C. The maximum criterion of α selectivity for limonene was 1.6 at 60°C. Chromatographic methods for the separation of enantiomers are used to determine the configuration of amino acids, to study racemization, as well as for preparative separation of enantiocidal substances. To date, there exists a large range of chiral stationary phases (CSP) of various nature used in gas chromatography. For example, phases based on chiral amino acids allow the recognition of enantiomers due to the formation of diastereomers between amino acid derivatives and the compounds to be separated. Chiral amino acids chemically coupled to polysiloxanes of Chirasil-Val brand are an example of such phases. Phases based on cyclodextrins are the most widely used as CSPs. However, despite the large number of advantages, such CSPs have a number of flaws: high noise signal, low thermal stability, and relatively short lifetime of chromatographic columns. Therefore, it is of interest to search for new stationary phases with enhanced enantioselectivity. In this connection, adsorbents based on supramolecular network structures look promising. It was previously established that sorbents based on one-component supramolecular structures of uracil, 5-hydroxy-6-methyluracil and melamine are capable of separating the enantiomers of menthol, camphene, and camphor. In this case, uracil and melamine taken in a molar ratio of 1:1 are able to form mixed supramolecular structure. The latter has a stable 3D structure with channels inside the threedimensional aggregate. Therefore, it is of interest to study the possibilities of a mixed supramolecular structure to chiral recognition.
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