Die Cu‐ und Ni‐Komplexe (III) werden wie aufgezeichnet aus den (S)‐Titelliganden (I), den entsprechenden Aminosäuren (II) sowie Cu(II)‐sulfat oder Ni(II)‐acetat in Gegenwart von NaOMe als chromatographisch trennbare Diastereomerengemische synthetisiert, in denen der Anteil des mit (S)‐Aminosäure gebildeten Komplexes durch erfolgte Epimerisierung überwiegt und für die Ni‐Komplexe größer als für die Cu‐Komplexe ist.
200ChemInform Abstract The stereoselectivity of the novel title reagent (III) in the retro-racemization of chelates synthesized from the reagent, the amino acids alanine, valine or phenylalanine and Ni2+ or Cu2+ is examined. The activity displayed by (III) is compared to that of the known chiral reagent (S)-2-N-(N'-benzylprolyl)aminobenzophenone. Both reagents are found to be almost equal in their activities. Employing these reagents α-amino acids are obtained in optical purities of 90-96%.
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