Oxy-/amino-difluoromethylthiolation of β,γ-unsaturated oximes/hydrazones have been developed for construction of HCF 2 S-containing isoxazolines and pyrazolines by employing PhSO 2 SCF 2 H as difluoromethylthiolation reagent under mild conditions. Such transformations exhibit good functional group tolerance and scalability. Possible mechanisms are proposed.

An oxidative dehydrogenative coupling of thiols with alkanes via direct C(sp 3 )−H bond functionalization to form a new C−S bond and S� O double bond was developed. The present reaction features the use of readily available reagents and high step-and atom-efficiency, thus providing an efficient access to sulfoxides. A possible mechanism is proposed.

Novel decarboxylative oxyacyloxylation of propiolic acids has been developed. This reaction provides an efficient access to alkynyl-containing α-acyloxy ketones from readily available starting materials and exhibits significant functional group tolerance. Furthermore, oxyacyloxylation of terminal alkynes and aliphatic propiolic acids was also developed. A possible reaction mechanism is proposed based on mechanistic studies.

Free radical carbochloromethylations of ortho-cyanoarylacrylamides and N-(arylsulfonyl)­acrylamides have been developed by employing simple alkyl chlorides as the chloromethyl source. The transformations are characterized by wide functional group compatibility and utilizing readily available reagents, thus providing efficient methods for constructing polychloromethyl-substituted quinoline-2,4-diones and α-aryl-β-polychloromethylated amides.

A copper-catalyzed cascade multicomponent reaction for synthesizing ditriazolyl diselenides from azides, terminal alkynes, and elemental selenium has been developed. The present reaction features utilizing readily available and stable reagents, high atom-economy, and mild reaction conditions. A possible mechanism is proposed.