The purpose of this study was to validate a method for analyzing gait patterns determined by the center of mass (CoM) using an accelerometer. [Subjects and Methods] A tri-axial accelerometer was attached to the lower back of 11 healthy young males. Vertical and lateral CoM displacement were assessed using the accelerometer and a 3D motion capture system under 8 different walking conditions. The validity of the accelerometer-based CoM was evaluated by comparison with the motion capture-based CoM using the intraclass correlation coefficient (ICC) and Bland-Altman analysis. [Results] ICCs corresponding to inter-rater reliability were good-to-excellent for vertical CoM displacement (0.73-0.94) and fair-to-good for lateral CoM displacement (0.31-0.71). However, Bland-Altman analysis revealed systematic bias, in which accelerometer-based CoM was overestimated. [Conclusion] The motion of the CoM measured by this accelerometer fixed to the trunk can be used for simplified analysis of human locomotion. The results demonstrate the great potential in clinical practice of accelerometry as a user-friendly, cost-effective and valid gait analysis tool.
Objective: To characterise changes in respiratory muscle strength, physical function, and dyspnoea in patients who underwent pre-and post-operative exercise intervention following lobectomy for non-small-cell lung cancer (NSCLC).
Methods: This retrospective study included NSCLC patients who underwent lobectomy via video-assisted thoracoscopic surgery (VATS) or posterolateral thoracotomy (PLT) and pre-and post-operative exercise intervention consisting of breathing, flexibility, resistance, aerobic exercises, coughing/huffing techniques, and early mobilisation. Maximum mouth inspiratory (Pimax) and expiratory pressures (Pemax), 6-min walk distance (6MWD), quadriceps force (QF), and modified Medical Research Council (mMRC) dyspnoea scale were evaluated preoperatively, at hospital discharge, and post-lobectomy 1 and 3 months. Results: Data from 41 patients were analysed. At hospital discharge, the Pimax, Pemax, 6MWD, and mMRC dyspnoea scores were lower than pre-operatively; QF remained unchanged; Pimax and 6MWD recovered to pre-operative values at post-lobectomy 1 month; and Pemax and mMRC dyspnoea scores recovered at 3 months. During subanalysis, Pimax and mMRC dyspnoea scores in the VATS (n = 24) and PLT groups (n = 17) recovered to pre-operative values at post-lobectomy 1 and 3 months. Conclusion: After lobectomy, respiratory muscle strength, physical function, and dyspnoea in patients who underwent exercise intervention returned to pre-operative values at post-lobectomy 3 months.
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