Tomographic image reconstruction using statistical methods can provide more accurate system modeling, statistical models, and physical constraints than the conventional filtered backprojection (FBP) method. Because of the ill posedness of the reconstruction problem, a roughness penalty is often imposed on the solution to control noise. To avoid smoothing of edges, which are important image attributes, various edge-preserving regularization methods have been proposed. Most of these schemes rely on information from local neighborhoods to determine the presence of edges. In this paper, we propose a cost function that incorporates nonlocal boundary information into the regularization method. We use an alternating minimization algorithm with deterministic annealing to minimize the proposed cost function, jointly estimating region boundaries and object pixel values. We apply variational techniques implemented using level-sets methods to update the boundary estimates; then, using the most recent boundary estimate, we minimize a space-variant quadratic cost function to update the image estimate. For the positron emission tomography transmission reconstruction application, we compare the bias-variance tradeoff of this method with that of a "conventional" penalized-likelihood algorithm with local Huber roughness penalty.
The statistics of photon counting by systems affected by deadtime are potentially important for statistical image reconstruction methods. We present a new way of analysing the moments of the counting process for a counter system affected by various models of deadtime related to PET and SPECT imaging. We derive simple and exact expressions for the first and second moments of the number of recorded events under various models. From our mean expression for a SPECT deadtime model, we derive a simple estimator for the actual intensity of the underlying Poisson process; simulations show that our estimator is unbiased even for extremely high count rates. From this analysis, we study the suitability of the Poisson statistical model assumed in most statistical image reconstruction algorithms. For systems containing 'modules' with several detector elements, where each element can cause deadtime losses for the entire module, such as block PET detectors or Anger cameras, the Poisson statistical model appears to be adequate even in the presence of deadtime losses.
In many transmission imaging geometries, the transmitted "beams" of photons overlap on the detector, such that a detector element may record photons that originated in different sources or source locations and thus traversed different paths through the object. Examples include systems based on scanning line sources or on multiple parallel rod sources. The overlap of these beams has been disregarded by both conventional analytical reconstruction methods as well as by previous statistical reconstruction methods. We propose a new algorithm for statistical image reconstruction of attenuation maps that explicitly accounts for overlapping beams in transmission scans. The algorithm is guaranteed to monotonically increase the objective function at each iteration. The availability of this algorithm enables the possibility of deliberately increasing the beam overlap so as to increase count rates. Simulated single photon emission tomography transmission scans based on a multiple line source array demonstrate that the proposed method yields improved resolution/noise tradeoffs relative to "conventional" reconstruction algorithms, both statistical and nonstatistical.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with đź’™ for researchers
Part of the Research Solutions Family.