Objectives: The purpose of this study was to investigate the influencing factors of perceived safety culture, nursing work environment, and professional self-concept on patient safety care activities of nurse in small-medium sized hospitals.Methods: A cross-sectional survey was used. Participants were 186 nurses in seven small-medium sized hospitals of a metropolitan city, in Korea. Data were analyzed using multiple linear regression analysis.Results: The influencing factors of the patient safety care activities were perceived patient safety culture and professional self-concept. These two factors explained for 15.1% of the patient safety acre activities.Conclusions: Based on the result of this study, it is necessary to build a good patient safety culture and to develop a positive professional self-concept. The establishment of a positive safety culture should be prioritized to quickly recognized and sensitively accept problems related to patient safety and actively carry out patient safety nursing activity. In order to improve the professional self-concept, it is necessary to increase the social performance for voluntary cooperation and to recognize the self-categorization that the group to which one belongs is distinguished from other groups.

Perceived safety culture and nursing work environment are considered important prerequisites for a patient safety activity. Patient safety is also associated with person-centered care; however, few studies apply the person-centered care framework which includes staff attributes and care environment. This study aimed to examine the canonical correlations of person-centered care factors, including professional self-concept, patient safety culture, nursing work environment, and patient safety activities of nurses working in small–medium-sized hospitals. A cross-sectional survey was used. Participants included 171 nurses from seven small–medium-sized hospitals in Busan metropolitan city, in Korea. Data were analyzed using descriptive statistics, t-test, one-way analysis of variance (ANOVA), Pearson’s correlation coefficients, and canonical correlations. Two significant canonical variates were found. First, better professional self-concept, a positive patient safety culture, and better nursing work environment were associated with better patient safety care activities. Second, a negative patient safety culture and healthy nursing work environment were associated with a lack of communication between medical staff. Person-centered framework factors such as staff attributes and care environment were positively associated with patient safety activities. Based on the results, nurses in small–medium-sized hospitals should be highly aware of their professional self-concept. Moreover, nurses should be equipped with psychological safety and a healthy work environment to enhance patient safety activities.