Hydatidosis is a zoonosis caused by Echinococcus granulosus . Humans are accidentally contaminated by ingesting the parasite´s eggs mainly released through the faeces from infected dogs. Hydatidosis affects the bone in 0.5 to 2% of cases, with 44% of these cases involving in the spine. Vertebral hydatidosis is rare and it represents the most frequent and most dangerous form of bone involvement. This manifestation is extremely delicate, difficult to correctly identify and manage. The authors report two cases of vertebral hydatidosis revealed by medullar compression and increasing lumbar-radicular pain and functional impotence of lower limbs. Imaging showed multicystic bony lesions in lumbar spine. The extension into the spinal canal and to the perivertebral soft tissue were involved in both cases. We present those two cases to highlight the role of radiological exploration for diagnosis especially with magnetic resonance imaging (MRI) and the importance of monitoring this dangerous pathology.
Background Penile metastases are very rare and arise most frequently from genitourinary cancers. Penile metastases from rectal adenocarcinoma are less common. Case presentation We report the case of a 47-year-old North Afican man with penile metastases from a rectal adenocarcinoma, which was discovered 4 months after abdominoperineal resection. A penile biopsy was carried out and established the metastatic nature. He underwent palliative chemotherapy treatment. He was still alive 4 months after diagnosis of penile metastases. Conclusion The prognosis of metastasis to the penis is very poor; the best results have been achieved with surgery but only for lesions where metastasis is limited to the penis.
A 54-years-old woman suffered from a bilateral pelvic and lumbar pain. She had a systemic investigation shows a diffuse bone lesions. A biopsy of iliac bone was done and revealed sarcoidosis. Bony manifestations of sarcoidosis are rare and challenging to diagnose. Our report shows that MRI with diffusion weighted sequences is a simple and non invasive technique to evaluate bone infiltration. It helps to distinguish inflammatory disease from metastatic lesions and to guide the osseous biopsy. Moreover, fluorodeoxyglucose PET scan, are useful in establishing the extent of damage and measuring disease activity.
Background: Primary breast lymphoma is a very rare disease. The diffuse large B cell subtype is the most common histological variety. The clinical presentation is non-specific; it can be similar to that found in breast carcinoma. The diagnosis is only retained after a definitive histological analysis. The management of these lymphomas is no different from that of other localizations. We report the case of primary breast diffuse large B cells lymphoma collected at the medical oncology department of the Hassan II Hospital of Fez in a 32-year-old patient. Through this work, we will discuss the epidemiological, clinical, paraclinical, histological, therapeutic, and prognostic characteristics of these tumors. Case presentation: A 32-year-old woman consulted for a left breast nodule evolving for 3 months. Clinical examination objectified a painless mass of the left breast without inflammatory signs and homolateral axillary adenopathy of 3cm. Mammography and breast ultrasound were performed objectifying three tissue lesions measuring 26mm for the largest in the left breast, associated with homolateral axillary adenopathy. A micro biopsy was performed. Histological analysis showed breast parenchyma largely dissociated by cell proliferation of diffuse architecture with large cells. In immunohistochemistry, tumor cells were positive for the anti-CD20 antibody. An extension assessment with thoracoabdominalcomputed tomographydid not show any secondary localization outside the breast lesions found in the mammography and ultrasound. Chemotherapy with R-CHOP was decided, but the patient refused to be treated for family reasons. Conclusion: Through this work, a case of DLBCL was reported with a review of the literature. In summary, the DLBCL histological subtype is the most frequent form of mammary lymphoma. Consolidation radiotherapy after conventional chemotherapy remains the most reasonable therapeutic modality for the treatment of patients with DLBCL. Large studies are necessary to identify the factors that influence survival, to improve the management of patients with these lymphomas.
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