A 32-year-old male with renal retinal dysplasia is presented. He also showed hearing loss and growth retardation. Laboratory data showed mild proteinuria, renal dysfunction and type-1 renal tubular acidosis. Computed tomography showed multiple cysts at the corticomeduUary junction of both kidneys. Ocular examinations disclosed retinitis pigmentosa. On light microscopy of renal biopsy specimens, diffuse cystic dilatation of Bowman’s space as well as dilated tubules with interstitial fibrosis and cellular infiltration were noted. Electron microscopy revealed a peculiar chromatin condensation of epithelial cell nuclei in Bowman’s capsules, glomeruli and tubules. The association of renal retinal dysplasia with diffuse glomerular cysts has not, to our knowledge, been previously reported.
Silver is used in various fields because of its high safety and broad antimicrobial spectrum. Here, the bactericidal activities of silver ion(Ag +)solution were compared to those of sodium hypochlorite(NaClO)in order to determine its usefulness as a disinfectant in hemodialysis. The minimum killing concentration(MKC)of each disinfectant was measured using the bacterial strains Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus. With bacteria isolated from product water manufacturing processes(tap water, activated carbon filter treatment water, and RO water)and the dialysis fluid line(B tank and dialysis fluid), antibacterial tests were conducted using each disinfectant. In terms of MKC, while Ag + solution was not as fast acting as NaClO, comparable bactericidal activities were observed over time. In particular, Ag + solution appears to be more effective than NaClO in disinfecting chlorine-resistant water-borne bacteria inside the product water manufacturing line. In addition, Ag + solution killed not only Gram-negative bacteria, but also Gram-positive bacteria. Thus, Ag + solution may be used as a disinfectant in hemodialysis and it appears to be as useful as NaClO. Possible use of silver ion solution as a disinfectant in hemodialysis 銀は安全性が高いことと抗菌スペクトルが広いことからさまざまな分野で使用されている.今回,銀イオン (Ag +)水の殺菌性を次亜塩素酸ナトリウム(NaClO)と比較し,Ag + 水の透析用消毒剤としての有用性を検討した. 試験菌株として Pseudomonas aeruginosa,Escherichia coli,Staphylococcus aureus を用いて各消毒剤の最小殺 菌濃度(MKC)を測定した.また,透析用水製造工程(原水,活性炭処理水,RO 水) ,透析液ライン(B タンク, 透析液)から検出された細菌に対して各消毒剤の殺菌効果試験を行った.MKC の結果から,Ag + 水は NaClO のよ
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