A ‘F'lurry of activity: The title reaction provides a convenient procedure for direct synthesis of perfluoroalkylated phosphines. The synthesized phosphine n‐C10F21PPh2 forms a complex with palladium(II) to give 1 and several runs of coupling reactions are attained with n‐C10F21PPh2 by using a fluorous/organic biphasic system.
A practical synthesis yielding P‐perfluoroalkylated phosphines from triarylphosphines and perfluoroalkyl iodides has been developed. The photoinduced reaction involves the substitution of aryl groups on the phosphorus atom with perfluoroalkyl groups to successfully afford P‐perfluoroalkylated phosphines. In addition, the P‐perfluoroalkylated phosphines were found to promote the Cu‐free cross‐coupling reaction of acid chlorides with terminal alkynes.magnified image
‘F’ steht für Aktivität: Durch die Titelreaktion können perfluoralkylierte Phosphane einfach und direkt synthetisiert werden. Das auf diesem Weg erhaltene Phosphan n‐C10F21PPh2 bildet mit einer Palladium(II)‐Vorstufe den Komplex 1, und der Ligand kann mehrere Male für eine Kupplungsreaktion wiederverwendet werden.
Palladium diacetate (Pd(OAc)2), in the presence of acetic acid, is found to exhibit excellent catalytic activity for the double hydroselenation of terminal alkynes with benzeneselenol to yield the corresponding diselenoketals regioselectively.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.