The first examples of rhodium-catalyzed carbonyl addition via hydrogen autotransfer are described, as illustrated in tandem butadiene-mediated carbonyl addition−redox isomerizations that directly convert primary alcohols to isobutyl ketones. Related reductive coupling−redox isomerizations of aldehyde reactants mediated by sodium formate also are reported. A doublelabeling crossover experiment reveals that the rhodium alkoxide obtained upon carbonyl addition enacts redox isomerization without dissociation of rhodium at any intervening stage.
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