Summary Malignant rhabdoid tumors (MRT) are rare, lethal tumors of childhood that most commonly occur in the kidney and brain. MRT are driven by SMARCB1 loss, but the molecular consequences of SMARCB1 loss in extra-cranial tumors have not been comprehensively described and genomic resources for analyses of extra-cranial MRT are limited. To provide such data, we used whole genome sequencing, whole genome bisulfite sequencing, whole transcriptome (RNA-Seq) and miRNA sequencing (miRNA-Seq), and histone modification profiling to characterize extra-cranial MRT. Our analyses revealed gene expression and methylation sub-groups and focused on dysregulated pathways, including those involved in neural crest development.

This paper presents a robust and efficient method for license plate detection with the purpose of accurately localizing vehicle license plates from complex scenes in real time. A simple yet effective image downscaling method is first proposed to substantially accelerate license plate localization without sacrificing detection performance compared with that achieved using the original image. Furthermore, a novel line density filter approach is proposed to extract candidate regions, thereby significantly reducing the area to be analyzed for license plate localization. Moreover, a cascaded license plate classifier based on linear support vector machines using color saliency features is introduced to identify the true license plate from among the candidate regions. For performance evaluation, a data set consisting of 3977 images captured from diverse scenes under different conditions is also presented. Extensive experiments on the widely used Caltech license plate data set and our newly introduced data set demonstrate that the proposed approach substantially outperforms state-of-the-art methods in terms of both detection accuracy and run-time efficiency, increasing the detection ratio from 91.09% to 96.62% while decreasing the run time from 672 to 42 ms for processing an image with a resolution of 1082×728 . The executable code and our collected data set are publicly available.

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In the era of Corona Virus Disease 2019 (COVID-19), wearing a mask can effectively protect people from infection risk and largely decrease the spread in public places, such as hospitals and airports. This brings a demand for the monitoring instruments that are required to detect people who are wearing masks. However, this is not the objective of existing face detection algorithms. In this article, we propose a two-stage approach to detect wearing masks using hybrid machine learning techniques. The first stage is designed to detect candidate wearing mask regions as many as possible, which is based on the transfer model of Faster_RCNN and InceptionV2 structure, while the second stage is designed to verify the real facial masks using a broad learning system. It is implemented by training a two-class model. Moreover, this article proposes a data set for wearing mask detection (WMD) that includes 7804 realistic images. The data set has 26403 wearing masks and covers multiple scenes, which is available at "https://github.com/BingshuCV/WMD." Experiments conducted on the data set demonstrate that the proposed approach achieves an overall accuracy of 97.32% for simple scene and an overall accuracy of 91.13% for the complex scene, outperforming the compared methods. Index Terms-Broad learning system (BLS), Corona Virus Disease 2019 (COVID-19), transfer learning, wearing mask detection (WMD). I. INTRODUCTION S INCE the first patient infected by Corona Virus Disease 2019 (COVID-19) has been identified in 2019, the virus spread the world very fast. It is quickly declared as a global Manuscript

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Single Shot MultiBox Detector (SSD) is one of the fastest algorithms in the current object detection field, which uses fully convolutional neural network to detect all scaled objects in an image. Deconvolutional Single Shot Detector (DSSD) is an approach which introduces more context information by adding the deconvolution module to SSD. And the mean Average Precision (mAP) of DSSD on PASCAL VOC2007 is improved from SSD's 77.5% to 78.6%. Although DSSD obtains higher mAP than SSD by 1.1%, the frames per second (FPS) decreases from 46 to 11.8. In this paper, we propose a single stage end-to-end image detection model called ESSD to overcome this dilemma. Our solution to this problem is to cleverly extend better context information for the shallow layers of the best single stage (e.g. SSD) detectors. Experimental results show that our model can reach 79.4% mAP, which is higher than DSSD and SSD by 0.8 and 1.9 points respectively.Meanwhile, our testing speed is 25 FPS in Titan X GPU which is more than double the original DSSD.

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