The prognostic significance of ascites in the dissemination of metastases in epithelial ovarian cancer (EOC) is unclear. Our study aimed to investigate the association between clinicopathological factors and the development of ascites, as well as its prognostic significance. Three hundred and thirty three patients with primary EOC were suitable for inclusion. We analyzed the correlation between clinicopathological factors, including the extent of metastases, and ascitic volume. The prognostic significance of ascites was assessed using the Kaplan-Meier method and multivariate Cox's regression analysis. The average ascitic volume was 1,800 ml. Significantly, more patients with advanced FIGO stage disease presented with ascites. The volume of ascites increased significantly when metastatic disease was present in more than three regions (p<0.05), and this was the sole factor identified as associated with ascitic volume by multiple linear regression analysis. Median survival was significantly different between those with an ascitic volume less than 1,800 ml (median survival = 58 months), and those with a volume greater than 1,800 ml (median survival = 28.6 months) (p<0.05). Subgroup analysis of stage III and IV patients also revealed a poor prognosis in the presence of massive ascites (p = 0.03). Multivariate analyses found that massive ascites and poor differentiation were independent poor prognostic factors for stage III and IV EOC patients by Cox regression, using a backward elimination procedure. The volume of ascites increased significantly with the extent of metastastic disease. Massive ascites and poor tumor differentiation were associated with a worse prognosis in patients with advanced stage ovarian cancer.

Objective: To evaluate the soluble TIM-3 (sTIM-3) expression level in oral squamous cell carcinoma (OSCC) and determine its clinical diagnostic potential. Methods: The sTIM-3 and squamous cell carcinoma antigen (SCCAg) levels of 199 OSCC patients and 107 healthy individuals were assessed using an enzyme-linked immunosorbent assay and their individual and combined efficiency rates were compared. Results: The results showed higher sTIM-3 and SCCAg levels in the OSCC patients and better diagnostic potential for a combination of these markers than for their individual assessments, as well as positive correlation of sTIM-3 levels with clinicopathological factors. Conclusion: sTIM-3 is a potential novel and readily accessible OSCC biomarker, which in combination with SCCAg expression level might better diagnose OSCC patients.

Objective : The purpose of this study was to investigate 55 cases of ossifying fibroma to analyze their clinical and pathological data. Methods : The clinical data, age, imaging performance, serology and their prognosis of 55 cases were analyzed and also Chi-square Test for statistical analysis were made. Results : The COF took up 70.9%, JPOF took up 20.0%, and JTOF took up 5.5%. 62.5% COF were the females, 75% JPOF concentrated in females, 66.7% JTOF concentrated in males. 66.7% COF located in the mandible. 54.5% JPOF were in the maxilla, in which 4 cases (4/11,36.4%) involved the para-nasal sinus. JTOF mainly concentrated in the mandible (66.7%). 2 cases (3.6%) exhibited multi-lesions. 7 cases (12.7%) were found the level of serum ALP up-regulated, and the up-regulation concentrated in younger patients (0~29 years) ( P <0.05). In radiographic presenting, only 7.3% displayed unclear borderline, and 87.3% exhibited mixed lesions, 7.3% was X-ray transparent, 5.5% was X-ray opaque. 29.1% had thinning bone cortex and 1 cases was found the bone cortex destructed (1/55,1.8%).18.2% OF appeared tooth displacement, and 9.1% displayed the amputated-like absorption of tooth root. 32 cases were followed up, 31.3% underwent conservative treatment suffered relapse, there was significant differences between the conservative and radical treatment ( P <0.05). Conclusions: The main subtype of OF was COF, JPOF and JTOF were relatively less. The majority of sporadic OF was single lesion, multi-lesions were rare. COF occurred with the female predilection in mandible, while JPOF occurred with the female predilection in maxilla; JTOF was the youngest, most occurred in adolescent males in mandible. Tooth displacement was often seen, and the root appeared as an amputated-like resorption. Younger patients were more likely to have elevated ALP. The patients underwent conservative curettage had relatively higher rate of relapse, the lesion should be resected radically to prevent relapse. Keywords: ossifying fibroma, clinical, pathological, jaw

The generator is the most popular mobile power device and backup power device in the world. It is very important for human life. Therefore, it is important to develop more efficient combustion technology in order to save energy and reduce air pollution. In this paper, a novel technology of hydrogen and oxygen compound gasoline fuel is developed. Hydrogen and oxygen gases are produced from an electrolytic cell and then mixed with the intake gasoline and air. The compound fuel is sucked into the engine combustion chamber. The hydrogen and oxygen gases can be produced immediately without any storage device of hydrogen. The experimental results show that this technology can increase the power generation and decrease emission pollution due to promoting combustion efficiency. In addition, the spark plug seat temperature increases due to higher heat value of hydrogen. This technique can reduce carbon monoxide and HC, but increase carbon dioxide. The research and development of this technique can achieve the goals of energy saving, emission reduction, relative safety, easy refitting and low refitting expense. Moreover, this research possesses academic innovation and industrial application.