Rationale:
Lhermitte–Duclos disease (LDD) is a rare tumor of the nervous system with a typical “tiger striped’” sign, but its features on functional magnetic resonance imaging (fMRI) are still inconclusive.
Patient concerns:
To explore the characteristics of LDDs using fMRI.
Diagnoses:
We report 3 cases of pathologically confirmed LDDs.
Interventions:
Three patients underwent brain tumor surgery.
Outcomes:
All the patients had a good prognosis.
Lessons:
Magnetic resonance spectroscopy and susceptibility-weighted imaging combined with conventional MRI can be used to better diagnose LDDs. Perfusion-weighted imaging is not specific for distinguishing cerebellar tumors. The combined application of fMRI and conventional MRI can improve the accuracy of LDD diagnoses.
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