Summary
Because clothing has the longest and most direct contact with human skin, it is important to carefully choose suitable fabrics for atopic patients who have disrupted skin. To evaluate the clinical effectiveness and biophysical properties of a newly developed silver‐loaded cellulose fabric with incorporated seaweed, we enrolled 12 subjects with mild to moderate atopic dermatitis into a clinical control study. The subjects wore a two‐piece garment (top and leggings), each piece of which was divided into two parts: one side was made of SkinDoctor® fabric, and the other of 100% cotton. Treatment efficacy was measured with the modified SCORing Atopic Dermatitis (mSCORAD) index, transepidermal water loss (TEWL) and the patients’ subjective impressions. All three of these measures had significantly better scores on the side covered with SkinDoctor. These results suggest that SkinDoctor is a beneficial fabric that can improve the comfort of patients with AD.
.Abstract: In order to investigate the effect of gallotannin treatment to ceramide-containing fabrics on atopic skin diseases, the agglomeration of standard protein BSA and the deactivation of model enzyme were examined. The gallotannin treated on ceramide-containing fabrics precipitated the standard protein, BSA, and therefore deactivated the model enzyme by 70% at 6% treatment concentration. Wash durability should be improved after around 5 cycles of washing. Clinical test of the gallotannin-treated fabrics was carried out on mice for two test items, transepidermal water loss assay and severity score of diseased skin of mice. The results showed significant level of improvement of atopic skin diseases compared with the negative controled.
This study investigates specific fabric structures with the optimal moisture transfer properties of moisture absorbency and dryness depending on the yarn type. Experiments were performed on the moisture absorbency and dryness of yarns with different cross sections (four channels, six channels, and regular round), yarn counts (i.e., denier), filament counts, textures (i.e., textured vs. flat), and structures (e.g., double-layer construction with different densities between the face and back sides). Polyester fiber was identified and determined to fulfill the above functions. Experiments were also performed to determine factors that affect the absorbency function of cotton and polyester microporous spun yarns: the yarn count (mono denier), total yarn denier, absorbent chemical concentration, and yarn crosssectional shape. Finally, experiments were carried out to compare the moisture absorbency and dryness of different yarn cross sections: four channels, six channels, and regular round.
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