In this study, we aimed to manufacture a patient-specific gel phantom combining threedimensional (3D) printing and polymer gel and evaluate the radiation dose and dose profile using gel dosimetry. Methods:The patient-specific head phantom was manufactured based on the patient's computed tomography (CT) scan data to create an anatomically replicated phantom; this was then produced using a ColorJet 3D printer. A 3D polymer gel dosimeter called RTgel-100 is contained inside the 3D printing head phantom, and irradiation was performed using a 6 MV LINAC (Varian Clinac) X-ray beam, a linear accelerator for treatment. The irradiated phantom was scanned using magnetic resonance imaging (Siemens) with a magnetic field of 3 Tesla (3T) of the Korea Institute of Nuclear Medicine, and then compared the irradiated head phantom with the dose calculated by the patient's treatment planning system (TPS). Results:The comparison between the Hounsfield unit (HU) values of the CT image of the patient and those of the phantom revealed that they were almost similar. The electron density value of the patient's bone and brain was 996±167 HU and 58±15 HU, respectively, and that of the head phantom bone and brain material was 986±25 HU and 45±17 HU, respectively. The comparison of the data of TPS and 3D gel revealed that the difference in gamma index was 2%/2 mm and the passing rate was within 95%.Conclusions: 3D printing allows us to manufacture variable density phantoms for patient-specific dosimetric quality assurance (DQA), develop a customized body phantom of the patient in the future, and perform a patient-specific dosimetry with film, ion chamber, gel, and so on.
In Korea, when replacing or discarding parts of a medical linear accelerator (linac), self-disposal is required in the consideration of the activity, but there is no standard regulation to manage radioactive waste. The aim of this study is to check the activity of each part to determine the disposal time according to the clearance level for self-disposal. The results of measuring the components of the linac head parts of the disposed Varian, Elekta, and Siemens equipment were reflected in the Monte Carlo simulation to confirm the radionuclide change according to the presence or absence of impurities. To confirm the degree of activation of the linac, the main radionuclides according to the time after the linac shutdown, considering the workloads of 40/80 Gy/day of 10/15 MV linac irradiated with beams for 10 years in the results of the simulation of the linac parts, and the radionuclide concentration was confirmed. As a result of applying the clearance level for self-disposal in the notice of the Korean Nuclear Safety (KINS) to each linac head part, most parts of the 10 MV linac could be dismantled after 1 month, and 15 MV target and primary collimators were stored after a long period of time before being dismantled. Although additional radionuclides were identified according to the presence or absence of impurities, the disposal timing for each part did not change significantly. In this study, the clearance level for self-disposal for each radionuclide was applied to activated parts by three manufacturers to confirm the self-disposal timing and predict the timing at which workers are not exposed to radiation during dismantling/disposal.
Three-dimensional printing technology has the advantage of facilitating the construction of complex three-dimensional shapes. For this reason, it is widely used in medical and radiological fields. However, few materials with high electron density similar to that of bone exist for fabricating a human phantom. In this study, commercially available filament materials were used with an FDM 3D printer to perform delivery quality assurance (DQA) and were evaluated for medical use. For the bone filament material, BaSO4 was synthesized in five ratios of 2%, 4%, 6%, 8%, and 10% with 40% PBAT and 50~58% PLA. The electron density for the 3D printing material fabricated was obtained using kV energy CT and compared with the electron density of human organs and bones. The radiation beam properties of the 3D printed structures were analyzed as films for treatment using a linear accelerator. As a result, by changing the infill density of the material, it was possible to produce a material similar to the density of human organs, and a homogeneous bone material with HU values ranging from 371 ± 9 to 1013 ± 28 was produced. The 3D printing material developed in this study is expected to be usefully applied to the development of a patient-specific phantom to evaluate the accuracy of radiotherapy.
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