Hybrid prostheses have recently been used as suitable treatment alternatives for edentulous individuals to restore the mastication mechanism. These prostheses utilize “All on four” concept, in which four implants are inserted into the jaw bone, and supported by a bar. Titanium is usually used in the fabrication of “All on four” parts due to its good mechanical properties. However, it has many drawbacks including esthetic impairment, casting issues, hypersensitivity reactions, stress shielding, and incompatibility with imaging techniques. These drawbacks have prompted researchers to find alternative materials (e.g., polymers). Recently, the new polymeric material PEEK has a major role in dentistry, due to its biocompatibility, shock-absorbing ability, and good mechanical properties. This work used the finite-element method to conduct stress–strain analysis on mandible rehabilitated with a hybrid prosthesis, using PEEK in the fabrication of “All on four” parts instead of titanium, using different densities of spongy bone. As the density of spongy bone is expected to influence the choice of “All on four” fabrication material. A 300 N vertical force was applied unilaterally, bilaterally, and anteriorly to stimulate the different mastication mechanisms. The results illustrated that PEEK material reduced the stresses and strains on bone tissues and increased the mucosal stress, compared to titanium. Consequently, this material was recommended to be used in the fabrication of “All on four” parts, especially in the low-density model. However, further research on PEEK implants and abutments is required in near future.

Introduction: The non-invasive nature of bioimpedance technique is the reason for the adoption of this technique in the wide field of bio-research. This technique is useful in the analysis of a variety of diseases and has many advantages. Cardiovascular diseases are the most dangerous diseases leading to death in many regions of the world. Vascular diseases are disorders that affect the arteries and veins. Most often, vascular diseases have greater impacts on the blood flow, either by narrowing or blocking the vessel lumen or by weakening the vessel wall. The most common vascular diseases are atherosclerosis, wall swelling (aneurysm), and occlusion. Atherosclerosis is a disease caused by the deposition of plaques on the inner vessel wall, while a mural aneurysm is formed as a result of wall weakness. The main objective of this study was to investigate the effects of vascular diseases on vessel impedance. Furthermore, this study aimed to develop the measurement of vessel abnormalities as a novel method based on the bioimpedance phenomenon. Methods: Mathematical models were presented to describe the impedance of vessels in different vascular cases. In addition, a 3D model of blood vessels was simulated by COMSOL MULTIPHYSICS.5, and the impedance was measured at each vascular condition. Results: The simulation results clarify that the vascular disorders (stenosis, blockage or aneurysm) have significant impact on the vessel impedance, and thus they can be detected by using the bio-impedance analysis. Moreover, using frequencies in KHz range is preferred in detecting vascular diseases since it has the ability to differentiate between the healthy and diseased blood vessel. Finally, the results can be improved by selecting an appropriate electrodes configuration for analysis. Conclusion: From this work, it can be concluded that bioimpedance analysis (BIA) has the ability to detect vascular diseases. Furthermore, the proposed mathematical models are successful at describing different cases of vascular disorders.

Fixed prostheses are appropriate treatment solutions for edentulous patients. In fixed prostheses, following “All on four”, titanium frameworks are commonly used to support the implants. However, the limitations of titanium have prompted researchers to search for alternative materials (e.g. polymers). This study applied finite element investigation to evaluate the stress distribution in the parts of fixed prosthesis and the surrounding bone tissue, using polymeric frameworks in place of titanium, and different densities of spongy bone. As, the success of fixed prosthesis was predicted to be influenced also by bone quality, particularly spongy bone density. Fixed prosthesis was constructed on edentulous mandible, then different frameworks (CFR-PEEK 60%, CFR-PEEK 30%, PEKK, and PEEK) were stimulated instead of titanium, under 300N unilateral and bilateral forces. Three densities of spongy bone were stimulated which are normal, low and high. The choice of framework material depended on the density of spongy bone. Moreover, PEEK framework showed the lowest stress values on bone tissues and the highest stress values on mucosa. All frameworks could be used in the fixed prosthesis, in the cases of normal and high densities of spongy bone. In low-density case, soft frameworks (PEKK and PEEK) were recommended to reduce the stresses generated on bone tissues.

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Introduction: Fixed prosthesis is an appropriate solution for edentulous patients. In fixed prostheses, following “All on four”, titanium frameworks are commonly used to support the implants. However, the limitations of titanium have prompted the researchers to search for alternative materials (e.g. polymers). The success of fixed prosthesis is predicted to be influenced also by bone quality, particularly spongy bone density. Purpose: This study applied finite element investigations to evaluate the stress distribution in the parts of fixed prosthesis and the surrounding bone tissue, using polymeric frameworks in place of titanium, and different densities of spongy bone.Materials &Methods: Fixed prosthesis was constructed on edentulous mandible, then different frameworks (CFR-PEEK 60%, CFR-PEEK30%, PEKK, and PEEK) were stimulated instead of titanium, using different densities of spongy bone, under 300N unilateral force. Results: The choice of framework material depended on the density of spongy bone. Moreover, PEEK framework showed the lowest stress values on bone tissues and the highest stress values on the mucosa. Conclusions: All frameworks could be used in the fixed prosthesis, in the cases of normal and high densities of spongy bone. In low-density case, soft frameworks (PEKK & PEEK) were recommended to reduce the stresses generated on bone tissues.