No abstract

A simple and practical method for the glycosylation of several acceptors with 2,3,4,6-tetra-O-benzyl-d-glucopyranosyl bromide was established by the promotion of phosphine oxide. The corresponding disaccharides were obtained in high yields with extremely high α-selectivities under almost neutral condition.

Mild and highly α-selective glycosylations of several acceptors with glycosyl phosphonium iodide, a glycosyl donor readily generated in situ from glycosyl acetate, proceeded smoothly to afford the corresponding disaccharides in high yields.

No abstract