Kawasaki disease (KD) is an acute febrile multisystem vasculitis and has been recognized to be one of the most common causes of acquired heart disease in children. KD with gastrointestinal bleeding is quite rare. We report a 12-month-old boy with KD complicated by gastrointestinal hemorrhage after using of high-dose of aspirin. Physicians caring for patients with KD should mindful on the signs and symptoms of aspirin toxicity including gastrointestinal hemorrhage. Starting or early switching to a low-dose aspirin treatment on KD should be considered.
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