A vehicle detection and classification system has been developed based on a low-cost triaxial anisotropic magnetoresistive sensor. Considering the characteristics of vehicle magnetic detection signals, especially the signals for low-speed congested traffic in large cities, a novel fixed threshold state machine algorithm based on signal variance is proposed to detect vehicles within a single lane and segment the vehicle signals effectively according to the time information of vehicles entering and leaving the sensor monitoring area. In our experiments, five signal features are extracted, including the signal duration, signal energy, average energy of the signal, ratio of positive and negative energy of x-axis signal, and ratio of positive and negative energy of y-axis signal. Furthermore, the detected vehicles are classified into motorcycles, two-box cars, saloon cars, buses, and Sport Utility Vehicle commercial vehicles based on a classification tree model. The experimental results have shown that the detection accuracy of the proposed algorithm can reach up to 99.05% and the average classification accuracy is 93.66%, which verify the effectiveness of our algorithm for low-speed congested traffic.
Girdin functions as an Akt phosphorylation enhancer (APE), which expedites the proliferation and survival of many types of tumours. However, the influence of Girdin on pancreatic cancer and the underlying molecular mechanisms have yet to be uncovered. Hence, in the present study, we sought to elucidate the function of Girdin in pancreatic cancer malignancy, particularly its role in pancreatic cancer cell proliferation, migration and apoptosis. Immunohistochemistry (IHC) was used to evaluate Girdin expression in pancreatic cancer tissues and to analyse its correlation with pathological grade. Girdin expression was further validated in pancreatic cancer cell lines (AsPC-1, BxPC-3 and PANC-1), and human pancreatic ductal epithelial (HPNE) cells were used as a control. Recombinant adenovirus vectors containing Girdin-siRNA were constructed to inhibit Girdin expression and were used in subsequent experiments to determine the effects of Girdin silencing on pancreatic cancer cells. Girdin silencing suppressed pancreatic cancer cell proliferation and induced pancreatic cancer cell apoptosis in vitro and in vivo. According to the results of further mechanistic investigations, Girdin may regulate cell processes through the phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) signalling pathway to exert additive effects on pancreatic cancer.
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