Orthogonal frequency division multiplexing (OFDM) is a promising technique for the broadband wireless communication system. However, the inter-sub-carrier-interference (ICI) produced by the phase noise of transceiver local oscillator is a serious problem. Bit error rate (BER) performance is degraded because the orthogonal properties between the sub-carriers are broken down. In this paper, ICI self-cancellation of data-conjugate method is studied to reduce ICI effectively. CPE (common phase error), ICI and CIR (carrier to interference power ratio) are derived and discussed by the linear approximation of the phase noise. Then, the system performance of the data-conjugate method is compared with those of the original OFDM and the conventional data-conversion method. As results, it can be shown that CPE becomes zero in the OFDM of the data-conjugate method. Besides, in the OFDM system with phase noise, the data-conjugate method can make remarkable improvement of the BER performance and it is better than the data-conversion method and the original OFDM with or without convolution coding.
Background Glabridin (Glab) is a bioactive component of licorice that can ameliorate diabetes, but its role in diabetic nephropathy (DN) has seldom been reported. Herein, we explored the effect and underlying mechanism of Glab on DN. Methods The bioactive component-target network of licorice against DN was by a network pharmacology approach. The protective effect of Glab on the kidney was investigated by a high-fat diet with streptozotocin induced-diabetic rat model. High glucose-induced NRK-52E cells were used for in vitro studies. The effects of Glab on ferroptosis and VEGF/Akt/ERK pathways in DN were investigated in vivo and in vitro using qRT-PCR, WB, and IHC experiments. Results Bioinformatics analysis constructed a network comprising of 10 bioactive components of licorice and 40 targets for DN. 13 matching targets of Glab were mainly involved in the VEGF signaling pathway. Glab treatment ameliorated general states and reduced FBG, HOMA-β, and HOMA-insulin index of diabetic rats. The renal pathological changes and the impaired renal function (the increased levels of Scr, BUN, UREA, KIM-1, NGAL, and TIMP-1) were also improved by Glab. Moreover, Glab repressed ferroptosis by increasing SOD and GSH activity, and GPX4, SLC7A11, and SLC3A2 expression, and decreasing MDA and iron concentrations, and TFR1 expression, in vivo and in vitro. Mechanically, Glab significantly suppressed VEGF, p-AKT, p-ERK1/2 expression in both diabetic rats and HG-induced NRK-52E cells. Conclusions This study revealed protective effects of Glab on the kidney of diabetic rats, which might exert by suppressing ferroptosis and the VEGF/Akt/ERK pathway.
Forests on Changbai Mountain provide important ecological and economic services to the eastern Eurasian Continent. During the past decades, many of the forests have been harvested, mainly with clearcutting methods. Since 1998, new forest policies have required that forests be harvested with selective cutting methods. This paper demonstrates how to use a decision support system, FORESTAR, to select harvesting targets at a landscape level and to determine cutting intensity and cycle at a stand level. The study site is the Baihe Forestry Bureau, a typical forestry enterprise in northeast China. Based on the considerations of costs, timber production, and landscape integrity, three options are used to select forests for harvesting. An index called Priority Order is used to sort out all the selected forest stands with the three options. A diameter transition matrix model is then used to simulate and compare outcomes of different cutting intensities and cycles. The two decision steps are integrated as an interactive decision-making loop. The final logging plans worked out with such a decision-making process facilitate the realization of spatially-and temporally-sound forest management. #
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.