A new trapping route has been used to synthesize MoxCoxC confined in carbon polyhedrons, through trapping PMo12 clusters into pre-synthesized ZIF-67 polyhedrons. The catalysts showed excellent performance for water splitting.

We have reported the synthesis of hierarchical whisker-on-sheet (HWS) NiCoP anchored on Ni foam with adjustable surface structure for efficient hydrogen evolution reaction (HER). The HWS NiCoP was obtained by controllable phosphidation of HWS Ni-Co-carbonates hydroxide precursor grown on Ni foam (NF). The experimental parameters were optimally tuned to understand the formation process of the precursor and to regulate the microstructure of the materials. The test results indicated that the HWS NiCoP/NF can produce a current density of 10 mA cm-2 (η10) at a low overpotential of 59 mV and a current density of 100 mA cm-2 (η100) at an overpotential of 220 mV for HER. Notably, upon surface activation with KOH, the HER performance of HWS NiCoP/NF could be dramatically enhanced with η10 and η100 values of 42 mV and 141 mV, respectively. The HWS NiCoP/NF showed a superior performance to NiCoP displaying other morphologies (sheets and wires etc.) The good performance of HWS NiCoP/NF should be attributed to their special whisker-on-sheet structures that are favourable for effective contact with the electrolyte. Also, hydrated metals can be formed on surface after the alkali treatment step, which is beneficial to moderate the bonding to hydrogen and thus, improve the HER activity. The present study will be indicative toward the construction of highly-efficient HER catalysts by regulating the structure of the materials.

The development of effective and low-cost catalysts for overall water splitting is essential for clean production of hydrogen from water. In this paper, we report the synthesis of cobalt-vanadium (Co-V) bimetal-based catalysts for the effective water splitting. The Co 2 V 2 O 7 ·xH 2 O nanoplates containing both Co and V elements were selected as the precursors. After the calcination under NH 3 atmosphere, the Co 2 VO 4 and Co/VN could be obtained just by tuning the calcination temperature. Electrochemical tests indicated that the Co-V bimetal-based materials could be used as active hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) catalyst by regulating their structure. The Co/VN showed good performance for HER with the onset potential of 68 mV and can achieve a current density of 10 mA cm −2 at an overpotential of 92 mV. Meanwhile, the Co 2 VO 4 exhibited the obvious OER performance with overpotential of 300 mV to achieve a current density of 10 mA cm −2 . When the Co 2 VO 4 and Co/VN were used as the anode and cathode in a twoelectrode system, respectively, the cell needed a voltage of 1.65 V to achieve 10 mA cm −2 together with good stability. This work would be indicative to constructing Co-V bimetalbased catalysts for the catalytic application.

2-D porous Ni3N-Co3N hybrids were prepared by initial controllable growth of ZIF-67 on Ni(OH)2 sheets followed by nitridation. The synergistic nitridation of Ni(OH)2 and ZIF-67, is demonstrated to be important for the formation of 2-D porous hybrids that can be used as a magnetically separable catalyst for hydrogenation reactions.

Background. The mechanistic aspects of the involvement of long noncoding RNAs (lncRNAs) in NETosis, the process of neutrophil extracellular trap (NET) formation in head and neck squamous cell carcinoma (HNSCC), lack comprehensive elucidation. The involvement of these molecules in the immune microenvironment and plausible HNSCC prognosis remain to see the light of the day. The plausible functioning of NETosis-related lncRNAs with their plausible prognostic impact in HNSCC was probed in this work. Methods. The scrutiny of lncRNAs linked to NETosis entailed the probing of twenty-four genes associated with the process employing Pearson’s correlation analysis on HNSCC patients’ RNA sequencing data from The Cancer Genome Atlas (TCGA) database. The application of univariate, least absolute shrinkage and selection operator (LASSO), and multivariate Cox regression analyses yielded a NETosis-related lncRNA signature that was subjected to probing for its suitability in prognosis employing survival and nomogram analyses. Results. The NETosis-related lncRNA signature inclusive of five lncRNAs facilitated patients to be segregated as high-risk and low-risk groups with the former documenting a poor prognosis. Regression unearthed that the risk score was an independent factor for prognosis. The receiver operating characteristic (ROC) or receiver operating characteristic curve analysis documented a one-year area under time-dependent ROC curve (AUC) value of 0.711 that is corroborative of the accuracy of this signature. Additional probing documented an evident enriching of immune-linked pathways in the low-risk patients, while the high-risk patients documented an immunologically “cold” profile as per the infiltration of immune cells. We verified lncRNA expression from our NETosis-related lncRNA signature in vitro, which reflects the reliability of our model to a certain extent. Moreover, we also verified the function of the lncRNA. We found that LINC00426 contributes to the innate immune cGAS-STING signaling pathway, which explain to some extent the role of our prognostic model in predicting “hot” and “cold” tumors. Conclusions. The plausible prognostic relevance of the NETosis-related lncRNA signature (with five lncRNAs) emerges that is suggestive of its promise in targeting HNSCC.