Most existing joint neural models for Information Extraction (IE) use local task-specific classifiers to predict labels for individual instances (e.g., trigger, relation) regardless of their interactions. For example, a VICTIM of a DIE event is likely to be a VICTIM of an AT-TACK event in the same sentence. In order to capture such cross-subtask and cross-instance inter-dependencies, we propose a joint neural framework, ONEIE, that aims to extract the globally optimal IE result as a graph from an input sentence. ONEIE performs end-to-end IE in four stages: (1) Encoding a given sentence as contextualized word representations;(2) Identifying entity mentions and event triggers as nodes; (3) Computing label scores for all nodes and their pairwise links using local classifiers; (4) Searching for the globally optimal graph with a beam decoder. At the decoding stage, we incorporate global features to capture the cross-subtask and cross-instance interactions. Experiments show that adding global features improves the performance of our model and achieves new state-of-the-art on all subtasks. As ONEIE does not use any language-specific feature, we prove it can be easily applied to new languages or trained in a multilingual manner. Our code and models for English, Spanish and Chinese are publicly available for research purpose 1 . PER Erdogan PER Abdullah Gul End-Position resigned Elect won person personExample: Prime Minister Abdullah Gul resigned earlier Tuesday to make way for Erdogan, who won a parliamentary seat in by-elections Sunday.

Polylactide (PLA) was melt blended with a biodegradable hyperbranched poly(ester amide) (HBP) to enhance its flexibility and toughness without sacrificing comprehensive performance. The advantage of using HBP was due to its unique spherical shape, low melt viscosity, and abundant functional end groups together with its easy access. Rheological measurement showed that blending PLA with as little as 2.5% HBP resulted in a 40% reduction of melt viscosity. The glass transition temperature (T g) of PLA in the blends decreased slightly with the increase of HBP content, indicating partial miscibility which resulted from intermolecular interactions via H-bonding. The H-bonding involving CO of PLA with OH and NH of HBP was evidenced by FTIR analysis for the first time. The HBP component, as a heterogeneous nucleating agent, accelerated the crystallization rate of PLA. Remarkably, with the increase of HBP content, the elongation at break of PLA blends dramatically increased without severe loss in tensile strength, even the tensile strength increased within 10% content of HBP. The stress−strain curves and the SEM photos of impact-fractured surface showed the material changed from brittle to ductile failure with the addition of HBP. Reasonable interfacial adhesion via H-bonding and finely dispersed particulate structure of HBP in PLA were proposed to be responsible for the improved mechanical properties.

No abstract

No abstract

No abstract

The use of botanicals and dietary supplements derived from natural substances as an adjunct to an improved quality of life or for their purported medical benefits has become increasingly common in the United States. This review addresses the safety assessment and regulation of food products containing these substances by the U.S. Food and Drug Administration (FDA). The issue of safety is particularly critical given how little information is available on the toxicity of some of these products. The first section uses case studies for stevia and green tea extracts as examples of how FDA evaluates the safety of botanical and herbal products submitted for consideration as Generally Recognized as Safe under the Federal Food, Drug, and Cosmetics Act. The 1994 Dietary Supplement Health Education Act (DSHEA) created a regulatory framework for dietary supplements. The article also discusses the regulation of this class of dietary supplements under DSHEA and addresses the FDA experience in analyzing the safety of natural ingredients described in pre-market safety submissions. Lastly, we discuss an ongoing interagency collaboration to conduct safety testing of nominated dietary supplements.

A facile and efficient strategy for the syntheses of novel hyperbranched poly(ether amide)s (HPEA) from multihydroxyl primary amines and (meth)acryloyl chloride has been developed. The chemical structures of the HPEAs were confirmed by IR and NMR spectra. Analyses of SEC (size exclusion chromatography) and viscosity characterizations revealed the highly branched structures of the polymers obtained. The resultant hyperbranched polymers contain abundant hydroxyl groups. The thermoresponsive property was obtained from in situ surface modification of abundant OH end groups with N-isopropylacrylamide (NIPAAm). The study on temperature-dependent characteristics has revealed that NIPAAm-g-HPEA exhibits an adjustable lower critical solution temperature (LCST) of about 34−42 °C depending on the grafting degree. More interestingly, the work provided an interesting phenomenon where the HPEA backbones exhibited strong blue photoluminescence.

No abstract