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Nanotechnology is considered to be a key technology that has an important influence on the emergence and development of a series of high-technologies in the 21st century. Due to its multidisciplinary nature, nanotechnology requires extensive multi-sector collaborations to foster more efficient development outcomes. This paper proposed a novel triple helix model to analyse the globalization of China’s nanotechnology innovation. This analytical framework will include three main aspects: first, the independent and interactive relationship among universities, governments, and industries; second, the vertical progress of globalization; and third, some influential innovative elements throughout the process. Afterwards, we demonstrate the model via a case study on the China International Nanotech Innovation Cluster. Finally, the paper summarizes the propelling roles and active impact three main entities played in the nanotechnology globalization process, as well as the trend and challenge of globalization. Findings offer helpful implications for the triple helix innovation in other industries.

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