Stimuli-responsive polymeric drug delivery systems are of great interest in anticancer research. Here, a reactive oxygen species (ROS)–responsive prodrug was prepared by thioketal linkage of poly(ethylene glycol) (PEG) and the anticancer drug doxorubicin (DOX).
A ROS-responsive low molecular weight hydrogel was fabricated and loaded with an anticancer drug and a photosensitizer for efficient chemo-photodynamic therapy.
Redox/ATP switchable theranostic nanoparticles (TNs) with precise specificity and controllable mobility were developed for the real-time monitoring of anticancer drug release.
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