Leucine-rich alpha⁃2 glycoprotein 1 (LRG1) is an important member of the leucine-rich repetitive sequence protein family. LRG1 was mainly involved in normal physiological activities of the nervous system, such as synapse formation, synapse growth, the development of nerve processes, neurotransmitter transfer and release, and cell adhesion molecules or ligand-binding proteins. Also, LRG1 affected the development of respiratory diseases, hematological diseases, endocrine diseases, tumor diseases, eye diseases, cardiovascular diseases, rheumatic immune diseases, infectious diseases, etc. LRG1 was a newly discovered important upstream signaling molecule of transforming growth factor⁃β (TGF⁃β) that affected various pathological processes through the TGF⁃β signaling pathway. However, research on LRG1 and its involvement in the occurrence and development of diseases was still in its infancy and the current studies were mainly focused on proteomic detection and basic animal experimental reports. We could reasonably predict that LRG1 might act as a new direction and strategy for the treatment of many diseases.
2D layered MXene (Ti3C2Tx) with high conductivity and pseudo-capacitance properties presents great application potential with regard to electrode materials for supercapacitors. However, the self-restacking and agglomeration phenomenon between Ti3C2Tx layers retards ion transfer and limits electrochemical performance improvement. In this study, a 3D porous structure of Ti3C2Tx was obtained by adding alkali to a Ti3C2Tx colloid, which was followed by flocculation. Alkaline-induced flocculation is simple and effective, can be completed within minutes, and provides 3D porous networks. As 3D porous network structures present larger surface areas and more active sites, ions transfer accelerates, which is crucial with regard to the improvement of the superior capacitance and rate performance of electrodes. The sample processed with KOH (K-a-Ti3C2Tx) exhibited a high capacity of approximately 300.2 F g−1 at the current density of 1 A g−1. The capacitance of the samples treated with NaOH and LiOH is low. In addition, annealing is essential to further improve the capacitive performance of Ti3C2Tx. After annealing at 400 °C for 2 h in a vacuum tube furnace, the sample treated with KOH (K-A-Ti3C2Tx) exhibited an excellent specific capacitance of approximately 400.7 F g−1 at a current density of 1 A g−1, which is considerably higher than that of pristine Ti3C2Tx (228.2 F g−1). Furthermore, after 5000 charge–discharge cycles, the capacitance retention rate reached 89%. This result can be attributed to annealing, which can further remove unfavourable surface groups, such as –F or –Cl, and then improve conductivity capacitance and rate performance. This study can provide an effective approach to the preparation of high-performance supercapacitor electrode materials.
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